Results 91 to 100 of about 477,305 (254)

Analysis of the giant genomes of Fritillaria (Liliaceae) indicates that a lack of DNA removal characterizes extreme expansions in genome size. [PDF]

open access: yes, 2015
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.Plants exhibit an extraordinary range of genome sizes,
Andrew R. Leitch   +18 more
core   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Substantiating rational parameters of a method for shrinkage ore stoping while developing thin- vein steeply inclined deposits [PDF]

open access: yes, 2018
Objective of the paper is to substantiate rational ore-stoping technique while using small wells in the context of thin-vein steeply inclined deposit mining.
Denyshchenko, Oleksandr   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Associations between concussion and more severe TBIs, mild cognitive impairment, and early-onset dementia among military retirees over 40 years

open access: yesFrontiers in Neurology
Background and objectivesAs the population of U.S. service members (SMs) who have sustained concussions and more severe traumatic brain injuries (TBIs) during military service ages, understanding the long-term outcomes associated with such injuries will ...
Jennifer N. Belding   +7 more
doaj   +1 more source

A Target Restricted Assembly Method (TRAM) for Phylogenomics [PDF]

open access: yes, 2010
While next generation sequencing technology can produce sequences covering the entire genome, assembly and annotation are still prohibitive steps for many phylogenomics applications.
Hugh M. Robertson   +2 more
core   +1 more source

BLAST: Correlations in the Cosmic Far-Infrared Background at 250, 350, and 500 microns Reveal Clustering of Star-Forming Galaxies

open access: yes, 2009
We detect correlations in the cosmic far-infrared background due to the clustering of star-forming galaxies in observations made with the Balloon-borne Large Aperture Submillimeter Telescope, BLAST, at 250, 350, and 500 microns.
Adelberger   +79 more
core   +3 more sources

External Shock Model for Gamma-Ray Bursts during the Prompt Phase [PDF]

open access: yes, 2000
The hard X-ray and gamma-ray phenomenology of gamma-ray bursts (GRBs) can be explained by an external shock model where a single relativistic blast wave interacts with the surrounding medium.
Dermer, Charles D.
core   +3 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Seedling and adult plant resistance to Pyricularia oryzae in Ethiopian rice cultivars

open access: yesActa Universitatis Sapientiae: Agriculture and Environment, 2020
Two separate experiments were done for seedling and adult resistance in rice varieties against blast. Each experiment consists of 20 varieties and is evaluated under artificial inoculation with blast.
Gerema Geleta   +6 more
doaj   +1 more source

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