Results 111 to 120 of about 24,885,885 (288)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Repeated low-level red light therapy for childhood myopia management

BMJ Open Ophthalmology
Background Myopia has emerged as a major global public health challenge, with an urgent need for effective treatment strategies. Repeated low-level red light (RLRL) therapy has recently gained attention as a promising approach, with an increasing number ...
Changhong Yu, Xian Yang, Shunmei Gao, Zhan Yu, Chengfang Li, Xuejiao Yang   +5 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Avaliação dos mecanismos fotobiológicos envolvidos na antinocicepção induzida pela terapia por diodo emissor de luz em camundongos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2013.A terapia por diodo emissor de luz (LEDT, do inglês Light-EmittingDiode Therapy) tem sido ...
Cidral Filho, Francisco José
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Low-level laser therapy parameters.

, 2016
Low-level laser therapy parameters.
Lucas Andreo Dias dos Santos (2615125), Nathalia Bernardes (2615119), Kátia De Angelis (85529), Beatriz Guimarães Ribeiro (2615116), Raquel Agnelli Mesquita-Ferrari (729744), Danielle da Silva Dias (2615122), Kristianne Porta Santos Fernandes (729745), Agnelo Neves Alves (2615113), Tatiane Matarazzo Cantero (2615128)   +8 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment of Alopecia with Low-Level Light Therapy

SKIN The Journal of Cutaneous Medicine
Low-level light therapy (LLLT) is a safe, non-invasive treatment for various alopecias, offering an alternative or adjunct to pharmacologic therapies. By using specific wavelengths, LLLT releases nitric acid, increases blood flow, inhibits DHT, stimulates follicular cells, enhances mitochondrial activity, and modulates inflammatory pathways.
Aysham Chaudry, Alec Lawson, Wilhelmina Lam, Alexandra DeVries, Robert Vanaria, Mark Nestor   +5 more
openaire   +1 more source

Low Level Light Therapy (LLLT) for the treatment and management of dental and oral diseases

, 2014
Low Level Light (Laser) Therapy (LLLT) is the direct application of light to stimulate cell and tissue responses (photobiomodulation) to promote healing, reduce inflammation and induce analgesia. Studies have demonstrated its application and efficacy for
Hadis, Mohammed; id_orcid, Michelle J Holder, Holder, Michelle, Palin, William; id_orcid, Mohammed A Hadis, Michael R Milward, William M Palin, Cooper, Paul, Paul R Cooper, Carroll, James D., James D Carroll, Milward, Michael   +11 more
core   +1 more source