Results 41 to 50 of about 10,778,698 (292)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Thermal and hydraulic characteristics of an air heater with modified delta flow obstructions

e-Prime: Advances in Electrical Engineering, Electronics and Energy, 2023
Air heaters are extensively used for various applications like space heating, drying of agricultural products etc. Air heaters are low efficient due to poor heat transfer properties of air.
Bronin Cyriac, Siddappa S. Bhusnoor
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Efficiency of the Building Heating System with the Use of Low-pressure Steam Electric Heaters

Trudy Universiteta
This study assesses the efficiency of low-pressure steam electric (LPSE) heaters in building heating systems. The goal is to justify and develop an energy-efficient, reliable alternative to traditional centralized and autonomous heating. Advantages of the pipeless system include reduced capital costs, lower heat losses, and improved operational ...
Rustam BUZYAKOV, Аli МЕKHTIYEV, Aleksei YURCHENKO, Nazym АLPYSBAYEVA, Arkadi BILICHENKO   +4 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Initial research on thermal decomposition of 98% concentrated hydrogen peroxide in thruster-like conditions

Engineering Science and Technology, an International Journal, 2022
The current research is focused on investigating the possibility of harnessing the thermal decomposition of highly concentrated Hydrogen Peroxide 98% i.e., utilizing a decomposition process initiated and maintained solely by a temperature source for low ...
Lukasz Mezyk, Zbigniew Gut, Kiran Mohan, Jan Kindracki, Grzegorz Rarata   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

ANALISA PENGARUH PENGOPERASIAN HPH (HIGH PRESSURE HEATER) PADA PERFORMA PLTU PC 400 MW [PDF]

, 2021
Pembangkit Listrik Tenaga Uap (Steam Power Plants), dimana pada Pembangkit tersebut menggunakan siklus rankine. Efisiensi siklus rankine sendiri dapat ditingkatkan dengan proses regenerasi, sistem regenerasi pada Pembangkit Listrik Tenaga Uap sendiri ...
Budhi Suyitno, Agus Salim, Salim, Agus, Suyitno, Budhi   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Typical Damage Prediction and Reliability Analysis of Superheater Tubes in Power Station Boilers Based on Multisource Data Analysis

Energies, 2022
The superheater and re-heater piping components in supercritical thermal power units are prone to creep and fatigue failure fracture after extensive use due to the high pressure and temperature environment.
Guangkui Liu, Xu Yang, Xisheng Yang, Kui Liang, Dong An, Di Wu, Xiaohan Ren   +6 more
doaj   +1 more source