Results 71 to 80 of about 459,286 (299)

No evidence for a recent genetic bottleneck in the endangered Sheko cattle breed (African Bos taurus) revealed by microsatellite analysis [PDF]

, 2009
Sheko is African taurine cattle, valued for its milk yield, adaptation to humid tsetse infested environment and trypanotolerance. We used 30 microsatellite markers in analyzing 30 DNA samples. We found high genetic diversity and no genetic bottlenecks in
Hailu Dadi, Hirofumi Hanada, Joram Mwacharo, Koh Nomura, Markos Tibbo, Takashi Amano, Yukimizu Takahashi   +6 more
core   +1 more source

BeamLoRA: Beam-Constraint Low-Rank Adaptation

Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
Due to the demand for efficient fine-tuning of large language models, Low-Rank Adaptation (LoRA) has been widely adopted as one of the most effective parameter-efficient fine-tuning methods. Nevertheless, while LoRA improves efficiency, there remains room for improvement in accuracy. Herein, we adopt a novel perspective to assess the characteristics of
Gu, Naibin, Zhang, Zhenyu, Liu, Xiyu, Fu, Peng, Lin, Zheng, Wang, Shuohuan, Sun, Yu, Wu, Hua, Wang, Weiping, Wang, Haifeng   +9 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

UniAD: A Real-World Multi-Category Industrial Anomaly Detection Dataset with a Unified CLIP-Based Framework

Information
Industrial image anomaly detection is critical for automated manufacturing. However, most existing methods rely on single-category training paradigms, resulting in poor scalability and limited cross-category generalization.
Junyang Yang, Jiuxin Cao, Chengge Duan
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Two-Stage Fine-Tuning of Large Vision-Language Models with Hierarchical Prompting for Few-Shot Object Detection in Remote Sensing Images

Remote Sensing
Few-shot object detection (FSOD) in high-resolution remote sensing (RS) imagery remains challenging due to scarce annotations, large intra-class variability, and high visual similarity between categories, which together limit the generalization ability ...
Yongqi Shi, Ruopeng Yang, Changsheng Yin, Yiwei Lu, Bo Huang, Yu Tao, Yihao Zhong   +6 more
doaj   +1 more source

GoRA: Gradient-driven Adaptive Low Rank Adaptation

NeurIPS ...
He, Haonan, Ye, Peng, Ren, Yuchen, Yuan, Yuan, Zhou, Luyang, Ju, Shucun, Chen, Lei   +6 more
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Compacter: Efficient Low-Rank Hypercomplex Adapter Layers

, 2021
accepted in NeurIPS ...
Mahabadi, Rabeeh Karimi, Henderson, James, Ruder, Sebastian   +2 more
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source