Results 121 to 130 of about 8,676,773 (167)
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0858 Real-World Experience and Satisfaction with Low-Sodium Oxybate in Narcolepsy: Interim Results from LYRICAL

SLEEP
Abstract Introduction Low-sodium oxybate (LXB; Xywav®) is approved by the US Food and Drug Administration to treat excessive daytime sleepiness (EDS) or cataplexy in patients ≥7 years of age with narcolepsy and adults with idiopathic hypersomnia.
Caroleen Drachenberg   +11 more
openaire   +1 more source

1011 Individualized Dosing with Low-Sodium Oxybate in Idiopathic Hypersomnia: Patient Voices from LYRICAL

SLEEPJ
Abstract Introduction In the US, low-sodium oxybate (LXB; Xywav®) is approved by the Food and Drug Administration for the treatment of idiopathic hypersomnia (IH) in adults, and has the option for individualized dosing. The LYRICAL study examined the real-world treatment experience of US adults
Caroleen Drachenberg   +10 more
openaire   +1 more source

0860 Subjective Sleep Quality with Low-Sodium Oxybate Treatment in Narcolepsy: Results from the DUET Study

SLEEP
Abstract Introduction Jazz DUET (Develop hypersomnia Understanding by Evaluating low-sodium oxybate Treatment) is a phase 4, prospective, multicenter, single-arm, multiple-cohort, open-label study (NCT05875974) evaluating the effectiveness of low-sodium oxybate (LXB, Xywav®) treatment on outcomes ...
R Sangal   +8 more
openaire   +1 more source

0853 Sleep Architecture with Low-Sodium Oxybate Treatment in Idiopathic Hypersomnia: Results from the DUET Study

SLEEP
Abstract Introduction Jazz DUET (Develop hypersomnia Understanding by Evaluating low-sodium oxybate Treatment) is a phase 4, prospective, multicenter, single-arm, multiple-cohort, open-label study (NCT05875974) evaluating the effectiveness of low-sodium oxybate (LXB, Xywav®) treatment on outcomes ...
Alyssa Cairns   +8 more
openaire   +1 more source

0851 Effectiveness and Safety of Low-Sodium Oxybate in Idiopathic Hypersomnia Participants: Results from the DUET Study

SLEEP
Abstract Introduction Introduction: Jazz DUET (Develop hypersomnia Understanding by Evaluating low-sodium oxybate Treatment) is a phase 4, prospective, multicenter, single-arm, multiple-cohort, open-label study (NCT05875974) evaluating the effectiveness of low-sodium oxybate (LXB, Xywav®) treatment on
David Plante   +10 more
openaire   +1 more source

0762 Improvements in Sleep Inertia with Low-Sodium Oxybate Treatment in Participants with Idiopathic Hypersomnia in the DUET Study

SLEEPJ
Abstract Introduction People with idiopathic hypersomnia often experience sleep inertia, characterized by profound difficulty waking up with grogginess, disorientation, and cognitive impairment immediately after awakening.
Deborah Nichols   +8 more
openaire   +1 more source

0852 Subjective Sleep Quality with Low-Sodium Oxybate Treatment in Idiopathic Hypersomnia: Results from the DUET Study

SLEEP
Abstract Introduction Jazz DUET (Develop hypersomnia Understanding by Evaluating low-sodium oxybate Treatment) is a phase 4, prospective, multicenter, single-arm, multiple-cohort, open-label study (NCT05875974) evaluating the effectiveness of low-sodium oxybate (LXB, Xywav®) treatment on outcomes ...
Richard Bogan   +8 more
openaire   +1 more source

0856 Real-World Patient Insights on Low-Sodium Oxybate for Idiopathic Hypersomnia: Interim Results from LYRICAL

SLEEP
Abstract Introduction Low-sodium oxybate (LXB; Xywav®) is approved by the US Food and Drug Administration to treat excessive daytime sleepiness or cataplexy in patients ≥7 years of age with narcolepsy and adults with idiopathic hypersomnia (IH).
Caroleen Drachenberg   +11 more
openaire   +1 more source

0632 Design Elements for a Switch Study from High- to Low-Sodium Oxybate Evaluating Blood Pressure in Narcolepsy (XYLO)

SLEEP
Abstract Introduction High sodium intake can increase blood pressure (BP) and future cardiovascular risk. Individuals with narcolepsy have an elevated cardiovascular comorbidity burden before considering medication-specific risks.
William White   +5 more
openaire   +1 more source

0639 Long-term Safety and Timing of Adverse Events with Low-Sodium Oxybate in a Phase 3 Idiopathic Hypersomnia Study

SLEEP
Abstract Introduction Low-sodium oxybate (LXB; Xywav®) is approved by the US Food and Drug Administration for the treatment of idiopathic hypersomnia in adults. To examine the long-term safety of LXB in this population, this post hoc analysis evaluated treatment-emergent adverse events (TEAEs) over ...
Richard Bogan   +4 more
openaire   +1 more source

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