Green spectrofluorimetric method for quantification of sodium oxybate in pharmaceutical and plasma samples [PDF]
Scientific ReportsSodium oxybate is a newly approved oral treatment for narcolepsy-related cataplexy and excessive daytime sleepiness. It has been misused recreationally and implicated in drug-facilitated crimes.
Reem M. Alnemari +8 more
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Once-Nightly Sodium Oxybate Meets American Academy of Sleep Medicine Criteria for Treatment of Narcolepsy. [PDF]
J Sleep ResABSTRACT Data from the REST‐ON trial were not available before the 2021 American Academy of Sleep Medicine (AASM) clinical practice guideline update, which included a literature review through August 2020. This post hoc analysis from REST‐ON assessed participants who achieved clinically significant improvements on individual AASM clinical significance ...
Ortiz LE +7 more
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Prophylactic effect of intraoperative sodium oxybate on postoperative delirium in older patients undergoing major orthopedic surgery: a randomized clinical trial [PDF]
BMC MedicineBackground Postoperative delirium (POD) represents a significant challenge in perioperative care, particularly among older surgical patients. This acute neuropsychiatric syndrome is associated with prolonged hospitalization, increased mortality, and long-
Meiying Cui +8 more
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Long-Term Treatment of Narcolepsy and Idiopathic Hypersomnia with Low-Sodium Oxybate [PDF]
Nature and Science of Sleep, 2023 Logan D Schneider,1 Anne Marie Morse,2 Michael J Strunc,3 Joyce K Lee-Iannotti,4 Richard K Bogan5 1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; 2Janet Weis Children’s Hospital, Geisinger ...
Schneider LD +4 more
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Reply to: Intraoperative use of sodium oxybate to prevent post-operative delirium in older patients undergoing major orthopedic surgery [PDF]
BMC MedicineBackground In our previously published article, we investigated the preventive efficacy of sodium oxybate against post-operative delirium (POD) in elderly patients undergoing orthopedic surgery and found that intraoperative sodium oxybate demonstrates ...
Meiying Cui, Hang Xue, Ping Zhao
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Intraoperative use of sodium oxybate to prevent postoperative delirium in older patients undergoing major orthopedic surgery [PDF]
BMC MedicineBackground This matters arising article addresses the recently published article in BMC Medicine by Cui et al., titled “Prophylactic effect of intraoperative sodium oxybate on postoperative delirium in older patients undergoing major orthopedic surgery ...
Fu-Shan Xue +2 more
doaj +2 more sources
Sodium Oxybate: a Substitute for Alcohol? [PDF]
European Psychiatry, 2022 Gamma-hydroxybutyrate (GHB) is a neurotransmitter found naturally in the human brain. Sodium oxybate (SO) is the sodium salt of GHB. In 2000 GHB was classified a Schedule I controlled substance, while SO became a Schedule III controlled substance for ...
A. Gual +3 more
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Once-nightly sodium oxybate (FT218) improved symptoms of disrupted nighttime sleep in people with narcolepsy: a plain language summary [PDF]
Journal of Comparative Effectiveness Research, 2023 What is this summary about? This is a plain language summary of a published article in the journal CNS Drugs. Narcolepsy is a rare sleep condition.
Thomas Roth +4 more
doaj +2 more sources
Sodium Oxybate-Induced secondary mania with psychotic symptoms: a case report and literature review [PDF]
European PsychiatryIntroduction Sodium oxybate, an effective treatment for narcolepsy-associated daytime sleepiness and cataplexy, has been extensively. Despite its therapeutic benefits, sodium oxybate is not without its risks, and adverse psychiatric effects have been ...
C. Cárdenes Moreno +5 more
doaj +2 more sources
Evaluation of pitolisant, sodium oxybate, solriamfetol, and modafinil for the management of narcolepsy: a retrospective analysis of the FAERS database [PDF]
Frontiers in PharmacologyObjectiveNarcolepsy, a rare neurological disorder believed to have an autoimmune etiology, necessitates lifelong management. This study aimed to provide evidence supporting the safety of pharmacological treatment for narcolepsy.MethodsFive-year data on ...
Xiaodan Zhou +5 more
doaj +2 more sources