Results 1 to 10 of about 5,885 (217)

A Case Report of Narcolepsy with Partial Cataplexy Misdiagnosed as Epilepsy

Türk Uyku Tıbbı Dergisi, 2015
Cataplexy is present in 70% of narcolepsy patients; narcolepsy with cataplexy is now named as narcolepsy type 1 in recent classification of sleep disorders. Cataplexy is defined as short lasting decrease or loss of muscle tone.
Gülçin Benbir Senel, Derya Karadeniz
doaj   +2 more sources

Automatic detection of cataplexy [PDF]

Sleep Medicine, 2018
Although being the most specific symptom of narcolepsy type 1 (NT1), cataplexy is currently investigated by clinical interview only, with potential diagnostic pitfalls. Our study aimed at testing the accuracy of an automatic video detection of cataplexy in NT1 patients vs.
Bartolini, Ilaria, Pizza, Fabio, Di Luzio, Andrea, Neccia, Giulia, Antelmi, Elena, Vandi, Stefano, Plazzi, Giuseppe   +6 more
openaire   +3 more sources

Cataplexy versus Pseudoseizure : A Case Study

Marshall Journal of Medicine, 2020
Cataplexy is frequently misdiagnosed as pseudo seizures. This case study about a young patient shows the necessary steps needed to accurately diagnose and treat cataplexy as well as understand the differences between narcolepsy Type I and Type II.
Sammar Atassi , Katherine Atassi
doaj   +3 more sources

Human narcolepsy is linked to degeneration of both locus coeruleus and hypocretin neurons [PDF]

Nature Communications
Earlier studies led to the conclusion that human narcolepsy with cataplexy was correlated with the loss of hypocretin (Hcrt = orexin) neurons in the hypothalamus.
Thomas C. Thannickal, Ming-Fung Wu, Marcia E. Cornford, Jerome M. Siegel   +3 more
doaj   +2 more sources

Dynamic Brain State Alterations in Narcolepsy: A Hidden Markov Model Approach to Thalamocortical Instability and Symptom‐Specific Neural Correlates [PDF]

Brain and Behavior, Volume 16, Issue 4, April 2026.
This graphical abstract illustrates how Hidden Markov modeling of functional magnetic resonance imaging (fMRI) reveals five dynamic brain states in narcolepsy type 1 (NT1), with reduced thalamocortical arousal (State 1) and elevated REM‐like limbic‐motor (State 4) and reward‐introspection (State 5) states linking to hallucinations and daytime ...
Wenyi Li, Lijing Jia, Xingyu Wang, Yuanhui Zhao, Zhenzhong Li, Zuojun Geng   +5 more
wiley   +2 more sources

Baclofen for narcolepsy with cataplexy: two cases

Nature and Science of Sleep, 2015
Elliott Kyung Lee,1,2 Alan Bruce Douglass1,2 1Department of Psychiatry, Faculty of Medicine, Institute of Mental Health Research, University of Ottawa, 2Royal Ottawa Mental Health Center, Ottawa, ON, Canada Abstract: Narcolepsy is a disabling sleep ...
Lee EK, Douglass AB
doaj   +1 more source

Treatment paradigms for cataplexy in narcolepsy: past, present, and future

Nature and Science of Sleep, 2015
Todd J Swick1–4 1Department of Neurology, University of Texas School of Medicine-Houston, Houston; 2The Sleep Center at North Cypress Medical Center, Cypress; 3Apnix Sleep Diagnostics, Houston; 4Neurology and Sleep Medicine Consultants, Houston, TX,
Swick TJ
doaj   +1 more source

2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C [PDF]

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot, Forbes D. Porter, Tatiana Bremova‐Ertl, Uma Ramaswami, Caroline Hastings, Bénédicte Héron, Justin Hopkin, Joella Melville, Hernan Amartino, Mireia del Toro, Federica Deodato, Fatih Ezgü, Paul Gissen, James B. Gibson, Can Ficicioglu, Roberto Giugliani, Orna Staretz‐Chacham, Frances Platt, Nathalie Guffon, Kristina Julich, Nikola Kresojević, Anna Lehman, Yann Nadjar, Susanne A. Schneider, Simon Jones, Eugen Mengel, Michel Tchan, Mark Walterfang, Ozlem Goker‐Alpan, Charlotte Dawson, Sandra Cowie, Toni Mathieson, Elizabeth Berry‐Kravis, Marc C. Patterson   +33 more
wiley   +2 more sources

The use of citalopram for the treatment of cataplexy

Sleep Science, 2014
This is a series of cases describing the use of citalopram for the treatment of cataplexy in patients with narcolepsy. Cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by ...
Hassana de Almeida Fonseca, Danielle Antunes Lopes, Danielle Pereira, Danilo Anunciatto Sguillar, Eduardo Lopes, Nilce Sanny Costa da Silva Behrens, Taís Figueiredo de Araújo Lima, Marcia Pradella-Hallinan, Juliana Castro, Sergio Tufik, Fernando Morgadinho Santos Coelho   +10 more
doaj   +2 more sources

Anomalous hypothalamic responses to humor in cataplexy. [PDF]

PLoS ONE, 2008
BackgroundCataplexy is observed in a subset of patients with narcolepsy and affects approximately 1 in 2,000 persons. Cataplexy is most often triggered by strong emotions such as laughter, which can result in transient, yet debilitating, muscle atonia ...
Allan L Reiss, Fumiko Hoeft, Adam S Tenforde, Wynne Chen, Dean Mobbs, Emmanuel J Mignot   +5 more
doaj   +2 more sources