Results 11 to 20 of about 8,772 (223)

Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice

open access: yesScientific Reports, 2023
Cataplexy is one of the symptoms of type 1 narcolepsy, characterized by a sudden loss of muscle tone. It can be seen as a behavioral index of salience, predominantly positive emotion, since it is triggered by laughter in humans and palatable foods in ...
Shigetaka Kawashima   +4 more
doaj   +1 more source

Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice

open access: yesCommunications Biology, 2021
Kuwaki and Kanno examine courtship behavior in orexin neuron-ablated mice (ORX-AB), which are a model of narcolepsy/cataplexy. They find that ORX-AB mice showed cataplexy-like behavior during both dark and light periods in response to a female encounter,
Tomoyuki Kuwaki, Kouta Kanno
doaj   +1 more source

The neurobiology of circadian rhythms [PDF]

open access: yes, 2009
Purpose of review There is growing awareness of the importance of circadian rhythmicity in various research fields. Exciting developments are ongoing in the field of circadian neurobiology linked to sleep, food intake, and memory.
Boersma, Gretha J.,   +2 more
core   +15 more sources

Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study [PDF]

open access: yes, 2013
Background: Gamma-hydroxybutyric acid (GHB), well known as a party drug, especially in Europe, is also legally used (sodium oxybate, Xyrem (R)) to treat a rare sleep disorder, narcolepsy with cataplexy.
Hertegonne, Katrien   +3 more
core   +1 more source

Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy

open access: yeseLife, 2019
Recent studies showed activation of the GABAergic neurons in the central nucleus of the amygdala (CeA) triggered cataplexy of sleep disorder narcolepsy.
Ying Sun   +5 more
doaj   +1 more source

Etiopathogenesis and Neurobiology of Narcolepsy: A Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Narcolepsy is a chronic lifelong sleep disorder and it often leaves a debilitating effect on the quality of life of the sufferer. This disorder is characterized by a tetrad of excessive daytime sleepiness, cataplexy (brief loss of muscle tone following ...
Swarup Kumar, Haritha Sagili
doaj   +1 more source

Treatment dilemmas in a young man presenting with narcolepsy and psychotic symptoms. [PDF]

open access: yes, 2011
Psychotic features can be present in both narcolepsy and psychosis, which can result in challenges in diagnosis and management. The prevalence of both conditions is low and the reports in young people are scarce. Our report illustrates the relevance of a
Davies, S, Fernandez, V, Walters, N
core   +2 more sources

The use of citalopram for the treatment of cataplexy

open access: yesSleep Science, 2014
This is a series of cases describing the use of citalopram for the treatment of cataplexy in patients with narcolepsy. Cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by ...
Hassana de Almeida Fonseca   +10 more
doaj   +1 more source

The functional role of dreaming in emotional processes [PDF]

open access: yes, 2019
Dream experience (DE) represents a fascinating condition linked to emotional processes and the human inner world. Although the overlap between REM sleep and dreaming has been overcome, several studies point out that emotional and perceptually vivid ...
Bartolacci, Chiara   +4 more
core   +2 more sources

Early detection of Niemann-pick disease type C with cataplexy and orexin levels: continuous observation with and without Miglustat

open access: yesOrphanet Journal of Rare Diseases, 2020
Study objectives Niemann-Pick type C (NPC) is an autosomal recessive and congenital neurological disorder characterized by the accumulation of cholesterol and glycosphingolipids.
A. Imanishi   +13 more
doaj   +1 more source

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