Narcolepsy and emotional experience: a review of the literature [PDF]
, 2018 Narcolepsy is a chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. This disease affects significantly the overall patient functioning, interfering with social, work, and ...
De Gennaro, Luigi +4 more
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Feeding-elicited cataplexy in orexin knockout mice [PDF]
, 2009 Mice lacking orexin/hypocretin signaling have sudden episodes of atonia and paralysis during active wakefulness. These events strongly resemble cataplexy, episodes of sudden muscle weakness triggered by strong positive emotions in people with narcolepsy,
Baumann, C R +4 more
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Diurnal fluctuation in the number of hypocretin/orexin and histamine producing: Implication for understanding and treating neuronal loss. [PDF]
, 2017 The loss of specific neuronal phenotypes, as determined by immunohistochemistry, has become a powerful tool for identifying the nature and cause of neurological diseases. Here we show that the number of neurons identified and quantified using this method
McGregor, Ronald +3 more
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Cataplexy versus Pseudoseizure : A Case Study
Marshall Journal of Medicine, 2020 Cataplexy is frequently misdiagnosed as pseudo seizures. This case study about a young patient shows the necessary steps needed to accurately diagnose and treat cataplexy as well as understand the differences between narcolepsy Type I and Type II.
Sammar Atassi , Katherine Atassi
doaj +1 more source
Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. [PDF]
, 2013 The neurochemical changes underlying human emotions and social behaviour are largely unknown. Here we report on the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amygdala ...
Behnke, Eric J +9 more
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Development of a head-mounted, eye-tracking system for dogs [PDF]
, 2011 Growing interest in canine cognition and visual perception has promoted research into the allocation of visual attention during free-viewing tasks in the dog. The techniques currently available to study this (i.e.
Guo, Kun, Mills, Daniel, Williams, Fiona
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Neurobiology of Disease, 2004 Cataplexy, an emotion-triggered sudden loss of muscle tone specific to narcolepsy, is tightly associated with hypocretin deficiency. Using hypocretin receptor 2 gene (hcrtr 2)-mutated narcoleptic Dobermans, we have previously demonstrated that altered ...
Mutsumi Okura +6 more
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Polymorphism located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 haplotype confer susceptibility to CNS hypersomnias (essential hypersomnia). [PDF]
PLoS ONE, 2009 BackgroundSNP rs5770917 located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 haplotype were previously identified as susceptibility loci for narcolepsy with cataplexy.
Taku Miyagawa +6 more
doaj +1 more source
Persistence of poor sleep predicts the severity of the clinical condition after 6months of standard treatment in patients with eating disorders [PDF]
, 2015 Clinical evidence suggests that eating disorder (ED) patients experience poor sleep even if they rarely complain of it. However, direct empirical evidence supporting this relationship is still sparse.
Battagliese, Gemma +3 more
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Case Reports in Neurological Medicine, 2012 Drop attacks are sudden spontaneous falls that are not accompanied by alteration of consciousness and are followed by immediate recovery. Cataplexy, which is usually associated with narcolepsy, is one of the causes of drop attacks.
Robert T. Egel +3 more
doaj +1 more source