Results 21 to 30 of about 4,469 (181)

Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice

open access: yesCommunications Biology, 2021
Kuwaki and Kanno examine courtship behavior in orexin neuron-ablated mice (ORX-AB), which are a model of narcolepsy/cataplexy. They find that ORX-AB mice showed cataplexy-like behavior during both dark and light periods in response to a female encounter,
Tomoyuki Kuwaki, Kouta Kanno
doaj   +1 more source

Etiopathogenesis and Neurobiology of Narcolepsy: A Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Narcolepsy is a chronic lifelong sleep disorder and it often leaves a debilitating effect on the quality of life of the sufferer. This disorder is characterized by a tetrad of excessive daytime sleepiness, cataplexy (brief loss of muscle tone following ...
Swarup Kumar, Haritha Sagili
doaj   +1 more source

The use of citalopram for the treatment of cataplexy

open access: yesSleep Science, 2014
This is a series of cases describing the use of citalopram for the treatment of cataplexy in patients with narcolepsy. Cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by ...
Hassana de Almeida Fonseca   +10 more
doaj   +1 more source

Early detection of Niemann-pick disease type C with cataplexy and orexin levels: continuous observation with and without Miglustat

open access: yesOrphanet Journal of Rare Diseases, 2020
Study objectives Niemann-Pick type C (NPC) is an autosomal recessive and congenital neurological disorder characterized by the accumulation of cholesterol and glycosphingolipids.
A. Imanishi   +13 more
doaj   +1 more source

Isolated Cataplexy in the Differential Diagnosis of Drop Attacks: A Case of Successful Clinical Diagnosis and Treatment

open access: yesCase Reports in Neurological Medicine, 2012
Drop attacks are sudden spontaneous falls that are not accompanied by alteration of consciousness and are followed by immediate recovery. Cataplexy, which is usually associated with narcolepsy, is one of the causes of drop attacks.
Robert T. Egel   +3 more
doaj   +1 more source

Cataplexy versus Pseudoseizure : A Case Study

open access: yesMarshall Journal of Medicine, 2020
Cataplexy is frequently misdiagnosed as pseudo seizures. This case study about a young patient shows the necessary steps needed to accurately diagnose and treat cataplexy as well as understand the differences between narcolepsy Type I and Type II.
Sammar Atassi , Katherine Atassi
doaj   +1 more source

The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans

open access: yesNeurobiology of Disease, 2004
Cataplexy, an emotion-triggered sudden loss of muscle tone specific to narcolepsy, is tightly associated with hypocretin deficiency. Using hypocretin receptor 2 gene (hcrtr 2)-mutated narcoleptic Dobermans, we have previously demonstrated that altered ...
Mutsumi Okura   +6 more
doaj   +1 more source

The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy

open access: yesFrontiers in Neuroscience, 2021
Narcolepsy is a sleep disorder caused by selective death of the orexin neurons that often begins in childhood. Orexin neuron loss disinhibits REM sleep during the active period and produces cataplexy, episodes of paralysis during wakefulness.
Alissa A. Coffey   +3 more
doaj   +1 more source

A Case Report of Narcolepsy with Partial Cataplexy Misdiagnosed as Epilepsy

open access: yesTürk Uyku Tıbbı Dergisi, 2015
Cataplexy is present in 70% of narcolepsy patients; narcolepsy with cataplexy is now named as narcolepsy type 1 in recent classification of sleep disorders. Cataplexy is defined as short lasting decrease or loss of muscle tone.
Gülçin Benbir Senel, Derya Karadeniz
doaj   +1 more source

Narcolepsy Patient Presenting as Drop Attack without Emotional Triggering and Subjective Sleepiness [PDF]

open access: yesSleep Medicine Research, 2016
Narcolepsy type I is characterized by excessive daytime sleepiness (EDS), cataplexy, sleep paralysis, hypnagogic hallucination, and fragmented night-time sleep.
Joon Hyun Baek, Ji-Ye Jeon, Sang-Ahm Lee
doaj   +1 more source

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