Results 31 to 40 of about 562,472 (163)

Decreased body mass index during treatment with sodium oxybate in narcolepsy type 1 [PDF]

, 2018
Narcolepsy type 1 is characterised by an increase in body weight after disease onset, frequently leading to obesity. It was suggested that this weight gain may be counteracted by treatment with sodium oxybate. We here provide longitudinal body mass index
Smolders, I.M., Donjacour, C.E., Wisse P. Meijden, Lammers, Gert Jan, Schinkelshoek, Mink S., Rolf Fronczek, Smolders, Isabelle M, Zwet, E.W. van, Donjacour, Claire E., Meijden, W.P. van der, Donjacour, Claire E H M, Gert Jan Lammers, Erik W. Zwet, van der Meijden, Wisse P, Mink S. Schinkelshoek, Isabelle M. Smolders, Fronczek, Rolf, Fronczek, R., Smolders, Isabelle M., Schinkelshoek, M.S., Lammers, G.J., Schinkelshoek, Mink S, van Zwet, Erik W., van der Meijden, Wisse P., van Zwet, Erik W, Claire E. Donjacour   +25 more
core   +1 more source

Calcium, Magnesium, Potassium, and Sodium Oxybates Oral Solution: A Lower-Sodium Alternative for Cataplexy or Excessive Daytime Sleepiness Associated with Narcolepsy

Nature and Science of Sleep, 2022
Yves Dauvilliers,1,2 Richard K Bogan,3 Karel Šonka,4 Markku Partinen,5 Nancy Foldvary-Schaefer,6 Michael J Thorpy7 1Sleep and Wake Disorders Centre, Department of Neurology, Gui de Chauliac Hospital, Montpellier, France; 2University of Montpellier ...
Dauvilliers Y, Bogan RK, Šonka K, Partinen M, Foldvary-Schaefer N, Thorpy MJ   +5 more
doaj  

Pharmacotherapy of Narcolepsy: Focus on Sodium Oxybate

, 2010
Narcolepsy is a complex disease with multiple symptoms that include excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. Pharmacologic management of patients with narcolepsy is based on treating these symptoms. Sodium
Sanjeev V. Kothare, Joseph Kaleyias
core   +1 more source

Sodium oxybate for excessive daytime sleepiness and sleep disturbance in Parkinson disease: A randomized clinical trial [PDF]

, 2018
IMPORTANCE: Sleep-wake disorders are a common and debilitating nonmotor manifestation of Parkinson disease (PD), but treatment options are scarce. OBJECTIVE: To determine whether nocturnal administration of sodium oxybate, a first-line treatment ...
Büchele, F, Maric, A, Omlor, W, Hackius, M, Hägele-Link, S, Baumann, CR, Imbach, LL, Waldvogel, D, Schreglmann, SR, Werth, E   +9 more
core   +2 more sources

Efficiency of sodium oxybate in episodic cluster headache

, 2013
We report the case of a 60-year-old man suffering from episodic cluster headache treated successfully with sodium oxybate.
Hidalgo, H, Kallweit, U, Uhl, V, Gantenbein, A R, Sándor, P S   +4 more
core   +1 more source

Successful Treatment of Narcolepsy and Cataplexy: A Review

Canadian Respiratory Journal, 2005
A 25-year-old woman with narcolepsy and cataplexy was treated with well-recognized drugs for these conditions. Because she did not respond, a decision was made to treat her with sodium oxybate.
B Lockrane, P Bhatia, Robin Gore
doaj   +1 more source

The cost-utility of sodium oxybate as narcolepsy treatment

, 2017
AIMS AND OBJECTIVES: Based on class-I studies, sodium oxybate is regarded as a first-line treatment for both EDS and cataplexy. The cost-effectiveness of sodium oxybate is largely unknown, though.
Kjellberg, J., Jennum, P., Wasling, Pontus,, H. Meinild, Wasling, P, J. Kjellberg, Jennum, P, P. Wasling, K. Bolin, P. Berling, Bolin, Kristian,, Bolin, K, Berling, P, Meinild, H., Meinild, H, P. Jennum, Berling, P., Kjellberg, J   +17 more
core   +1 more source

Sodium oxybate plus nalmefene for the treatment of alcohol use disorder: A case series.

, 2016
The treatment of alcohol use disorder still remains a challenge. The efficacy of the combined pharmacological treatment for alcohol use disorder has been widely investigated with controversial results.
BERNARDI, MAURO, Addolorato, G, D'Amore, Antonio, Maremmani, Angelo G. I., Caputo, F, Caputo, Francesco Maria, Caputo, Fabio, Addolorato, Giovanni, Maremmani, A, D’Amore, A, DOMENICALI, MARCO, Zoli, Giorgio, Maremmani, Icro, Zoli, G   +13 more
core   +1 more source

The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy [PDF]

, 2015
Contains fulltext : 154173.pdf (Publisher’s version ) (Closed access)Patients suffering from narcolepsy type 1 show altered skin temperatures, resembling the profile that is related to sleep onset in healthy controls.
Donjacour, CEHM Claire, Pijl, H., Heide, A., Donjacour, C.E., Fronczek, R Rolf, Reijntjes, Robert H A M, Overeem, S Sebastiaan, Lammers, Gert Jan Gert, van der Heide, A., Someren, EJW van, Reijntjes, R.H., Fronczek, R., Someren, van, E.J.W., van Someren, E.J.W., Lammers, G.J., Overeem, S.; id_orcid, Someren, E.J.W. van, Pijl, Hanno, Donjacour, C.E.H.M., van der Heide, A Astrid, Heide, A. van der, Overeem, S., Reijntjes, R.H.A.M.   +22 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source