Results 31 to 40 of about 626 (142)

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome [PDF]

, 2015
Gamma-hydroxybutyrate (GHB) is a short chain fatty acid endogenously produced within the central nervous system (CNS) and acts as a precursor and metabolite of the inhibitory neurotransmitter γ-aminobutyric acid (GABA).
KYRIAKOU, CHRYSTALLA, NAPOLETANO, SIMONA, ZAAMI, Simona, BUSARDO', FRANCESCO PAOLO, MARINELLI, Enrico   +4 more
core   +1 more source

RESTORE: Once-nightly oxybate dosing preference and nocturnal experience with twice-nightly oxybates

Sleep Medicine: X
Objective/Background: Preference for extended-release, once-nightly sodium oxybate (ON-SXB, FT218) vs twice-nightly immediate-release (IR) oxybate was assessed in participants switching from IR oxybate to ON-SXB in an open-label/switch study, RESTORE ...
Asim Roy, Thomas Stern, John Harsh, J. Douglas Hudson, Akinyemi O. Ajayi, Bruce C. Corser, Emmanuel Mignot, Adrian Santamaria, Anne Marie Morse, Brian Abaluck, Sally Ibrahim, Paula K. Schweitzer, Katie Lancaster, Jordan Dubow, Jennifer Gudeman   +14 more
doaj   +1 more source

Decreased body mass index during treatment with sodium oxybate in narcolepsy type 1

, 2018
Narcolepsy type 1 is characterised by an increase in body weight after disease onset, frequently leading to obesity. It was suggested that this weight gain may be counteracted by treatment with sodium oxybate. We here provide longitudinal body mass index
Smolders, I.M., Donjacour, C.E., Wisse P. Meijden, Lammers, Gert Jan, Schinkelshoek, Mink S., Rolf Fronczek, Smolders, Isabelle M, Zwet, E.W. van, Donjacour, Claire E., Meijden, W.P. van der, Donjacour, Claire E H M, Gert Jan Lammers, Erik W. Zwet, van der Meijden, Wisse P, Mink S. Schinkelshoek, Isabelle M. Smolders, Fronczek, Rolf, Fronczek, R., Smolders, Isabelle M., Schinkelshoek, M.S., Lammers, G.J., Schinkelshoek, Mink S, van Zwet, Erik W., van der Meijden, Wisse P., van Zwet, Erik W, Claire E. Donjacour   +25 more
core   +1 more source

iSPHYNCS: Unsupervised Clustering in Questionnaires and Metadata Reveals Distinct Subtypes in the Narcolepsy Borderland

Journal of Sleep Research, EarlyView.
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand, Livia Fregolente, Julia van der Meer, Elena S. Wenz, Annina Helmy, Lorenzo Brigato, Jan D. Warncke, Kseniia Zub, Ramin Khatami, Zhongxing Zhang, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Ulf Kallweit, Gert Jan Lammers, Athina Tzovara, Claudio L. A. Bassetti, Stavroula Mougiakakou, Markus H. Schmidt   +19 more
wiley   +1 more source

Diagnostic Value of Psychomotor Vigilance Task for Severe Sleep Inertia in Idiopathic Hypersomnia Versus Other Sleep Disorders Without Sleep Inertia

Journal of Sleep Research, EarlyView.
Diagnostic Value of PVT for Severe Sleep Inertia in Idiopathic Hypersomnia. ABSTRACT Sleep inertia impairs performance upon awakening and may be assessed using the psychomotor vigilance task (PVT). This study aimed to determine optimal PVT lapse cut‐offs at awakening to objectively measure sleep inertia by comparing patients with idiopathic hypersomnia
Elisa Evangelista, Alexandre Derré, Lucie Barateau, Anna Laura Rassu, Sofiene Chenini, Isabelle Jaussent, Yves Dauvilliers   +6 more
wiley   +1 more source

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin, Kinga Igloi, Alison Montagrin, Samika Kumar, Jeremy Hofmeister, Markus Gschwind, Sophie Schwartz, Virginie Sterpenich   +7 more
wiley   +1 more source

The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy

, 2015
Contains fulltext : 154173.pdf (Publisher’s version ) (Closed access)Patients suffering from narcolepsy type 1 show altered skin temperatures, resembling the profile that is related to sleep onset in healthy controls.
Donjacour, CEHM Claire, Pijl, H., Heide, A., Donjacour, C.E., Fronczek, R Rolf, Reijntjes, Robert H A M, Overeem, S Sebastiaan, Lammers, Gert Jan Gert, van der Heide, A., Someren, EJW van, Reijntjes, R.H., Fronczek, R., Someren, van, E.J.W., van Someren, E.J.W., Lammers, G.J., Overeem, S.; id_orcid, Someren, E.J.W. van, Pijl, Hanno, Donjacour, C.E.H.M., van der Heide, A Astrid, Heide, A. van der, Overeem, S., Reijntjes, R.H.A.M.   +22 more
core   +1 more source

Surveillance of Pharmaceutical Risk‐Mitigation Behavior: Applying and Comparing Statistical Process Control Methods Using Real World Data

Learning Health Systems, Volume 10, Issue 3, July 2026.
ABSTRACT Introduction Active post‐marketing surveillance of prescribing behavior of high‐risk drugs may provide early warning of unforeseen issues in a population, yet analysis approaches for surveillance using real‐world data are underdeveloped.
Harris Butler, John D. Rice, Nichole E. Carlson, Elaine H. Morrato   +3 more
wiley   +1 more source

Reply to: Intraoperative use of sodium oxybate to prevent post-operative delirium in older patients undergoing major orthopedic surgery

BMC Medicine
Background In our previously published article, we investigated the preventive efficacy of sodium oxybate against post-operative delirium (POD) in elderly patients undergoing orthopedic surgery and found that intraoperative sodium oxybate demonstrates ...
Meiying Cui, Hang Xue, Ping Zhao
doaj   +1 more source