Results 51 to 60 of about 1,224,792 (212)

Brazilian guidelines for the treatment of narcolepsy [PDF]

, 2010
Este artigo relata as conclusões da reunião de consenso com médicos especialistas sobre diagnóstico de narcolepsia baseada na revisão dos artigos sobre narcolepsia listados no Medline entre 1980 e 2010.
Alves, Rosana Cardoso, Alóe, Flávio, Araújo, John Fontenele, Azevedo, Alexandre, Bacelar, Andrea, Bezerra, Márcio, Bittencourt, Lia Rita Azeredo, Bustamante, Guilherme, Cardoso, Tânia Aparecida Marchiori de Oliveira, Eckeli, Alan Luiz, Fernandes, Regina Maria França, Goulart, Leonardo, Hasan, Rosa, Lopes, Maria Cecília, Minhoto, Gisele Richter, Moraes, Walter, Moreira, Gustavo Antônio, Pachito, Daniela, Pedrazolli Neto, Mário, Pinto Júnior, Luciano Ribeiro, Poyares, Dalva Lúcia Rollemberg, Pradella-Hallinan, Márcia, Prado, Lucila, Rizzo, Geraldo, Rodrigues, Raimundo Nonato Delgado, Roitman, Israel, Sander, Heidi Haueisen, Silva, Ademir Baptista, Tavares, Stella Márcia Azevedo   +28 more
core   +4 more sources

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4 butanediol (1,4-BD; BDO) : a literature review with a focus on UK fatalities related to non-medical use [PDF]

, 2015
Misuse of gamma hydroxybutrate (GHB) and gamma butyrolactone (GBL) has increased greatly since the early 1990s, being implicated in a rising number of deaths.
Abanades, Abanades, Absalom, ACMD, Adinoff, Akins, Al-Samarrie, Altose, Andresen, Andresen, Andresen-Streichert, Andresen-Streichert, Arena, Aromatario, Atha, Atha, Barbara Loi, Barker, Baselt, Beghè, Bennett, Bessman, Black, Blanchflower, Bluelight, Bluet-Pajot, BNF, Borgen, Borgen, Bosch, Bosman, Bourne, Boyd, Brailsford, Brenneisen, Brunt, Burch, Busardò, Cagnin, Caldicott, Caputo, Caputo, Carai, Carter, Catalano, Cheston, Chien, Chin, Christine Goodair, Coleman, Collier, Colombo, Colombo, Cook, Corkery, Corkery, Corkery, Couper, Couper, Couper, Couper, Couper, Crookes, Daily Mail, Dargan, Dargan, Davies, Davis, de Fiebre, DEA, DEA, DEA, Dhani, Dick, Dietze, Divry, DPA, Drugs-Forum, Dudek, Duer, Dunn, Dupont, Durgahee, Dyer, Dyer, Elian, Elliott, Elliott, Elliott, Elliott, Elliott, EMCDDA, EMCDDA, EMCDDA, EMCDDA, EMCDDA, EMCDDA, EMEA, EMEA, Erowid, Erowid, Erowid, Erowid, Evans, Fabrizio Schifano, Fadda, Feigenbaum, Ferrara, Ferrara, Ferrara, Fieler, FIRE, Franchitto, Frase, Friedman, Gahr, Galicia, Gallimberti, Gallimberti, Gallimberti, Galloway, Galloway, Galloway, Gerot Lannach Pharma GmbH., Gerra, Gheshlaghi, Gianutsos, Goodwin, Guidotti, Hagemann, Hansard, Harty, Hechler, Helrich, Herbert, Heytens, Hibell, Hibell, Hibell, Hodges, Hoes, Home Office, Home Office, Hopkins, Horyniak, Hugh Claridge, Hunter, Itzhak, John M. Corkery, Jones, Jones, Kalasinsky, Kam, Kamal, Kapil, Karch, Kaufman, Keating, Kelly, Kilgore, Kim, Kintz, Kintz, Knudsen, Korb, Korf, Kraner, Krul, Kugelberg, Laboratorio Farmaceutico C.T. Srl., Laborit, Laborit, Laborit, Lamb, Langford, LeBeau, Lenz, LeTourneau, Lettieri, Liechti, Liechti, Louagie, Luby, Lycaeum, Maitre, Maitre, Mamelak, Mamelak, Maremmani, Mari, Marinetti, Marinetti, Marston, Mason, Mazarr-Proo, McCabe, McCambridge, McCusker, McDaniel, McDonough, McDowell, Measham, Measham, Meyer, Meyer, Mikelsson, Mindandmuscle, Miotto, Miró, Mixmag, Mixmag, Mixmag, Morbidity and Mortality Weekly Report, Moriya, Moriya, Morse, Mozayani, Munir, Murali, Mégarbane, Nava, Navarro, Neels, Nelson, Nutt, Németh, ONDCP, ONS, ONS, ONS, Ornella Corazza, Ortega-Albás, Our Insight, O’Connell, Palamar, Palatini, Pan, Pazos, Penberthy, Poldrugo, Poldrugo, Poldrugo, Pounder, Quang, Quang, Rahbeeni, ReDNet., Reisch, Roberts, Romanelli, Rossetti, Roth, Roth, Roth, Roth, Roth, Rønning, Sakurada, Samokhvalov, Sanguineti, Schifano, Schmitt, Schneidereit, Sevak, Sewell, Shannon, Shima, Shröck, Simon Elliott, Simonsen, Sindicich, Sivilotti, Skala, Smith, Snead, Snead, Snead, Snead, Snead, Sporer, Stephens, Stephens, Strickland, Sturman, Sumnall, Takahara, Teter, Thai, Thai, Theron, Thomas, U.S. Xyrem® Multicenter Study Group, Uys, van Amsterdam, van Amsterdam, van Noorden, van Rij, Van Sassenbroeck, Van Sassenbroeck, van Vugt, Vayer, Vayer, Vickers, Vree, Wang, Wang, Wang, Ward, Weißhaar, Wellendorph, WHO, Williams, Winstock, Winstock, Winstock, Winstock, Wojtowicz, Wood, Wood, Wood, Yeatman, Zapata, Zvosec, Zvosec, Zvosec   +324 more
core   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

iSPHYNCS: Unsupervised Clustering in Questionnaires and Metadata Reveals Distinct Subtypes in the Narcolepsy Borderland

Journal of Sleep Research, EarlyView.
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand, Livia Fregolente, Julia van der Meer, Elena S. Wenz, Annina Helmy, Lorenzo Brigato, Jan D. Warncke, Kseniia Zub, Ramin Khatami, Zhongxing Zhang, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Ulf Kallweit, Gert Jan Lammers, Athina Tzovara, Claudio L. A. Bassetti, Stavroula Mougiakakou, Markus H. Schmidt   +19 more
wiley   +1 more source

Why dried blood spots are an ideal tool for CYP1A2 phenotyping [PDF]

, 2014
Background and Objective: Dried blood spot (DBS) sampling has gained wide interest in bioanalysis during the last decade and has already been successfully applied in pharmacokinetic and phenotyping studies.
De Kesel, Pieter, Lambert, Willy, Stove, Christophe   +2 more
core   +2 more sources

RESTORE: Once-nightly oxybate dosing preference and nocturnal experience with twice-nightly oxybates

Sleep Medicine: X
Objective/Background: Preference for extended-release, once-nightly sodium oxybate (ON-SXB, FT218) vs twice-nightly immediate-release (IR) oxybate was assessed in participants switching from IR oxybate to ON-SXB in an open-label/switch study, RESTORE ...
Asim Roy, Thomas Stern, John Harsh, J. Douglas Hudson, Akinyemi O. Ajayi, Bruce C. Corser, Emmanuel Mignot, Adrian Santamaria, Anne Marie Morse, Brian Abaluck, Sally Ibrahim, Paula K. Schweitzer, Katie Lancaster, Jordan Dubow, Jennifer Gudeman   +14 more
doaj   +1 more source

Sialidosis type I: How to alleviate disabling myoclonic seizures?—A multicenter analysis of eight cases and review of the literature

Epilepsia Open, Volume 11, Issue 2, Page 577-591, April 2026.
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat, I‐Chun Lee, Marica Rubino, Vehap Topçu, Melissa Chavez‐Castillo, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique‐Dunham, Manouela Valtcheva, Astrid Adarmes‐Gómez, Daniel Macias‐Garcia, Laura Laura Muñoz‐Delgado, Silvia Jesús, Pablo Mir, Andreas Merkenschlager, Antonietta Coppola   +15 more
wiley   +1 more source

Restorative sleep predicts the resolution of chronic widespread pain: results from the EPIFUND study [PDF]

, 2016
PublishedJournal ArticleMulticenter StudyResearch Support, Non-U.S. Gov'tVersion of record of article published in Rheumatology (Oxford). 2008 Dec; 47(12): 1809–1813. Published online 2008 Oct 7. doi: 10.1093/rheumatology/ken389OBJECTIVES: Poor sleep is
Davies, KA, Dickens, Chris, Macfarlane, GJ, McBeth, J, Morriss, R, Nicholl, BI, Ray, D   +6 more
core   +1 more source

Implication of the thalamus in sleep alterations observed in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is frequently accompanied by sleep disturbances. Alterations of sleep, in both quality and quantity, contribute to the progression of AD neuropathology. The thalamus, through its diverse nuclei, plays a central role in sleep regulation and sleep‐dependent memory ...
Carla Burnet‐Merlin, Y. Audrey Hay, Aurélie Brécier   +2 more
wiley   +1 more source