Results 221 to 230 of about 727,784 (263)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Persistent atrial fibrillation with left atrial low-voltage area: who benefit from additional modification? [PDF]

Europace
Zhang H, Chen N, Bian Q, Yuan M, Yang G, Shen Y, Chen H, Ju W, Li M, Gu K, Wu N, Liu H, Chen M.   +12 more
europepmc   +1 more source

Serum Vasoactive Intestinal Peptide as a Novel Biomarker for Low-Voltage Areas in Patients With Atrial Fibrillation. [PDF]

J Am Heart Assoc
Nishino K, Temma T, Natsui H, Watanabe M, Nakao M, Kawasaki M, Shimano K, Kawakami K, Saito S, Koya J, Tatsuta D, Koizumi T, Kadosaka T, Koya T, Tsuneta S, Kamiya K, Nagai T, Anzai T.   +17 more
europepmc   +1 more source

Reference dataset for semi-urban and rural Norwegian low voltage distribution grids. [PDF]

Data Brief
Engan LM, Ekrheim S, Bjarghov S, Klemets JRA, Schytte I, Kjølle G.   +5 more
europepmc   +1 more source

Optimization of Low-Voltage p-GaN Gate HEMTs for High-Efficiency Secondary Power Conversion. [PDF]

Micromachines (Basel)
Zhai L, Li X, Ji J, Yu L, Chen L, Chen Y, Xia H, Han Z, Wang J, Jiang X, Yuan S, Zhang T, Hao Y, Zhang J.   +13 more
europepmc   +1 more source

Perovskite Thin-Film Transistors for Ultra-Low-Voltage Neuromorphic Visions. [PDF]

Adv Sci (Weinh)
Rong Y, Yu, Zhang X, Wang T, Wang J, Li Y, Zhao T, He R, Gao Y, Huang C, Xiao S, Qin J, Bai S, Zhu H, Liu A, Chen Y, Song Q.   +16 more
europepmc   +1 more source