Results 131 to 140 of about 14,986,572 (302)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
The Low Voltage and Low Power Switch Mode Power Amplifier
, 2004 A low voltage and low power switch mode power amplifier is proposed. It is designed using TSMC 0.35\uce\ubcm 2p4m CMOS process technology. It can be applied to hearing aids, and the supply voltage is 1.5V.
Chen, Wei-chung
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Dynamic and Leakage Power-Composition Profile Driven Co-Synthesis for Energy and Cost Reduction
, 2004 Recent research has shown that combining dynamic voltage scaling (DVS) and adaptive body bias (ABB) techniques achieve the highest reduction in embedded systems energy dissipation [1].
Al-Hashimi, Bashir M +2 more
core +1 more source
A 51 to 65 GHz low-power bulk-pumped mixer using 0.13-?m CMOS Technology
, 2013 [[abstract]]A low-voltage and low-power down-conversion bulk-driven mixer using standard 0.13 mum CMOS technology is presented in this letter. To work on a low supply voltage and low power consumption applications while maintaining reasonable performance,
Che-Yu Wang;Jeng-Han Tsai
core
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Multi-Stage buck strategy for power management of triboelectric nanogenerators. [PDF]
Nat CommunGao Y +11 more
europepmc +1 more source