Results 121 to 130 of about 84,951 (308)

Drainage Fluid Amylase as a Biomarker for the Detection of Anastomotic Leakage After Low Anterior Resection of Rectal Cancer: A Two-center Study [PDF]

Yasuhiro Ishiyama, Yasumitsu Hirano, Misuzu Yamato, Sohei Akuta, Masatoshi Yoshizawa, Takatsugu Fujii, Naoto Okazaki, Chikashi Hiranuma, Shinichi Sakuramoto   +8 more
openalex   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Drain fluid iodine as a biomarker of anastomotic leak after low anterior resection in patients undergoing Gastrografin rectal tube flushes and omission of a diverting ileostomy: The GUSH study [PDF]

David A. Clark, Karen Dobeli, Darren R Allen, Brett McWhinney, Michael Lonne, Aleksandra Edmundson, Aleksandra Edmundson   +6 more
openalex   +1 more source

Anastomotic perfusion assessment with indocyanine green in robot-assisted low-anterior resection, a multicenter study of interobserver variation [PDF]

, 2023
Pernille Øhlenschläger Larsen, Nikolaj Nerup, Jesper N. Andersen, Niclas Dohrn, Mads Klein, Steffen Brisling, Soren Salomon, Per Vadgaard Andersen, Sören Möller, Morten Bo Søndergaard Svendsen, Hans B. Rahr, Lene Hjerrild Iversen, Ismail Gögenür, Niels Qvist, Mark Bremholm Ellebæk   +14 more
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Major Low Anterior Resection Syndrome (LARS) and Quality of Life in Patients With Low Rectal Cancer: A Preoperative Survey Using LARS Score and European Organisation for Research and Treatment of Cancer’s 30-Item Core Quality of Life Questionnaire [PDF]

, 2023
Ly Huu Phu, Hồ Tất Bằng, Nguyen Viet Binh, Hoang Danh Tan, Ung Van Viet, Nguyen Trung Tin   +5 more
openalex   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Defunctioning ileostomy and mechanical bowel preparation may contribute to development of low anterior resection syndrome

Videosurgery and Other Miniinvasive Techniques, 2018
Michał M. Nowakowski, Mateusz Rubinkiewicz, Natalia Gajewska, Grzegorz Torbicz, Michał Wysocki, Piotr Małczak, Piotr Major, Mateusz Wierdak, Andrzej Budzyński, Michał Pędziwiatr   +9 more
doaj   +1 more source

A Cap Polyposis Operated by Laparoscopy Assisted Low Anterior Resection: A Case Report

, 2009
Masakazu Tokunaga, Satoshi Ikeda, Jiro Okiyama, Takao Hinoi, Masanori Yoshimitsu, Makoto Yoshida, Daisuke Sumitani, Yuji Takakura, Masazumi Okajima, Hideki Ohdan   +9 more
openalex   +2 more sources