Results 171 to 180 of about 83,095 (256)

Machine learning prediction of anastomotic leak after low anterior resection: Nationwide database analysis. [PDF]

open access: yesMedicine (Baltimore)
Sakamoto T   +8 more
europepmc   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi   +12 more
wiley   +1 more source

Non-Restorative Low Anterior Resection Is Associated with Poor Intermediate-Term Oncological Outcomes in MRI-Defined Rectal Cancer. [PDF]

open access: yesCancers (Basel)
Geitenbeek RTJ   +5 more
europepmc   +1 more source

Bowel symptoms and self-care strategies of survivors in the process of restoration after low anterior resection of rectal cancer [PDF]

open access: gold, 2018
Lishi Yin   +11 more
openalex   +1 more source

Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC

open access: yesAdvanced Science, EarlyView.
Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 ...
Xiangui Meng   +6 more
wiley   +1 more source

Additional file 1 of Assessment of the risk of permanent stoma after low anterior resection in rectal cancer patients

open access: gold, 2020
Marcin Zeman   +5 more
openalex   +1 more source

Simultaneously Diagnosed and Successfully Treated Rectovaginal and Vesicovaginal Fistulae after Low Anterior Resection with Concomitant Resection of Female Genitalia [PDF]

open access: gold, 2017
Chisato Takagi   +7 more
openalex   +1 more source

Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

open access: yesAdvanced Science, EarlyView.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li   +14 more
wiley   +1 more source

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