An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Deep impact analysis of surgical strategy changes guided by indocyanine green fluorescence angiography in laparoscopic low anterior resection for rectal cancer. [PDF]
Qiu X +6 more
europepmc +1 more source
Laparoscopy-assisted posterior low anterior resection of rectal cancer [PDF]
Hao Qu +4 more
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This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao +17 more
wiley +1 more source
A 2-year prospective study on the evolution of Low Anterior Resection Syndrome (LARS) following rectal cancer surgery. [PDF]
Lauwereins L +12 more
europepmc +1 more source
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li +9 more
wiley +1 more source
Robotic Versus Laparoscopic Low Anterior Resection: Comparison of Peri-Operative Outcomes at United Lincolnshire Teaching Hospitals NHS Trust. [PDF]
Bhat NA +6 more
europepmc +1 more source
Rectovaginal fistula after low anterior resection in Chinese patients with colorectal cancer
Hongtu Zheng +6 more
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Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen +16 more
wiley +1 more source
Comparative perioperative outcomes of articulated versus conventional straight devices in laparoscopic low anterior resection: a propensity score-matched analysis. [PDF]
Lee H +7 more
europepmc +1 more source

