Results 31 to 40 of about 813,093 (318)

Proprioception and Geriatric Low Back Pain

Spine Surgery and Related Research, 2022
Proprioception is a deep sensation that perceives the position of each part of the body, state of movement and muscle contraction, and resistance and mass applied to the body. Proprioceptive feedback influences movement and positional accuracy, resulting
Yoshihito Sakai, Tsuyoshi Watanabe, Norimitsu Wakao, Hiroki Matsui, Naoaki Osada, Takaya Sugiura, Yoshifumi Morita, Keitaro Kawai, Tadashi Ito, Kazunori Yamazaki   +9 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Motor Control Changes in Low Back Pain: Divergence in Presentations and Mechanisms.

Journal of Orthopaedic and Sports Physical Therapy, 2019
SYNOPSIS Compared to healthy individuals, patients with low back pain demonstrate differences in all aspects of trunk motor control that are most often studied as differences in muscle activity and kinematics.
J. Dieën, N. P. Reeves, G. Kawchuk, G. Kawchuk, L. V. Dillen, P. Hodges   +5 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Short term effects of changes in air pollutant concentrations during peaks traffic hours on hospitalization for respiratory diseases

Scientific Reports
Research on the impact of changes in air pollutant concentrations during peak traffic hours on hospital admissions for respiratory diseases (RD) is limited. This study utilized a distributed lag nonlinear model (DLNM) to investigate this effect.
Wancheng Zhang, Ye Ruan, Jianglong Ling
doaj   +1 more source

Core outcome measurement instruments for clinical trials in nonspecific low back pain

Pain, 2017
To standardize outcome reporting in clinical trials of patients with nonspecific low back pain, an international multidisciplinary panel recommended physical functioning, pain intensity, and health-related quality of life (HRQoL) as core outcome domains.
Alessandro Chiarotto, M. Boers, R. Deyo, R. Buchbinder, Terry P. Corbin, L. Costa, N. Foster, M. Grotle, B. Koes, F. Kovacs, C. Lin, C. Maher, A. Pearson, W. Peul, M. Schoene, D. Turk, M. V. van Tulder, C. Terwee, R. Ostelo   +18 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

A study of the correlation between meteorological factors and hospitalization for acute lower respiratory infections in children

BMC Public Health
Background The study focuses on the effect of temperature and relative humidity on hospitalization for acute lower respiratory tract infections (LRTI) in children, respectively.
Wancheng Zhang, Ye Ruan, Jianglong Ling, Lei Wang   +3 more
doaj   +1 more source

Brain functional connectivity changes by low back extension pain model in low back pain patients.

PLoS ONE, 2020
PURPOSE:Low back pain (LBP) is a common ailment in most developed countries. Because most cases of LBP are known as 'non-specific', it has been challenging to develop experimental pain models of LBP which reproduce patients' clinical pain.
Seulgi Eun, Jeungchan Lee, Eun-Mo Song, Alexandra De Rosa, Jun-Hwan Lee, Kyungmo Park   +5 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source