Results 41 to 50 of about 399,631 (295)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Pain relief is associated with decreasing postural sway in patients with non-specific low back pain

, 2012
Background Increased postural sway is well documented in patients suffering from non-specific low back pain, whereby a linear relationship between higher pain intensities and increasing postural sway has been described.
Walker Bruce, Ruhe Alexander, Alexander Ruhe, Ruhe, A., Bruce Walker, Walker, B., Fejer, R., Fejer René, René Fejer, Fejer, René   +9 more
core   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Outcome of low back pain patients referred to orthopeadic outpatient clinic [PDF]

, 2014
Background: Musculoskeletal complaints are the commonest encounters in primary care. Low back pain management is commonly initiated by the family practitioner.
Borg, Joe, Grech, Stephan, Cuschieri, Sarah   +2 more
core  

The stigmatisation of people with chronic back pain [PDF]

, 2006
This study responded to the need for better theoretical understanding of experiences that shape the beliefs, attitudes and needs of chronic back patients attending pain clinics.
Sofaer-Bennett, Beatrice, Holloway, I., Beatrice Sofaer-Bennett, Sofaer-Bennett, B., Immy Holloway, Holloway, Immy, Walker, Jan, Walker, J., Jan Walker   +8 more
core   +1 more source

Low back pain

Revista Dor
BACKGROUND AND OBJECTIVES: Neuropathic pain is present in 37 to 55% of cases of low back pain. Neuropathic pain is associated with more intense pain, more severe comorbidities and worse quality of life.
Patrick Raymond Nicolas André Ghislain Stump, Ricardo Kobayashi, Alexandre Walter de Campos   +2 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Individuals with low back pain: how do they view physical activity? [PDF]

, 1999
Background. Recent guidelines for those with acute low back pain have advocated early resumption of normal activity and increased physical activity. Little is known about the relationship between low back pain and physical activity, and on the impact of ...
Moffett, Jennifer Klaber, Keen, Steven, Williams, Rhys, Tovey, Phil, Dowell, Antony C., Hurst, Keith   +5 more
core  

Occupational health guidelines for the management of low back pain: an international comparison

, 2003
The enormous socioeconomic burden of low back pain emphasises the need for effective management of this problem, especially in an occupational context.
Koes, Bart; id_orcid, Staal, J B, Hlobil, H., van Tulder, MW; id_orcid, van Tulder, MW, Waddell, G., Staal, JB, Burton, A.K., van Mechelen, W, Koes, B. W., van Tulder, M.W., Koes, B.W., Staal, J. B., Staal, J.B., van Mechelen, W., Burton, A K, Van Tulder, M. W., Burton, AK, Koes, Bart, Burton, A. Kim, Koes, B W, Burton, A. K., van Tulder, M W, Hlobil, H, Waddell, G, Waddell, Gordon   +25 more
core   +1 more source