Results 51 to 60 of about 1,082,608 (346)

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone [PDF]

, 2019
Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) until bone is remodeled. The interconnected osteocyte network within the
Vrahnas, Christina, Blank, Martha, Dite, Toby A, Tatarczuch, Liliana, Ansari, Niloufar, Crimeen-Irwin, Blessing, Nguyen, Huynh, Forwood, Mark R, Hu, Yifang, Ikegame, Mika, Bambery, Keith R, Petibois, Cyril, Mackie, Eleanor J, Tobin, Mark J, Smyth, Gordon K, Oakhill, Jonathan S, Martin, T John, Sims, Natalie A   +17 more
core   +1 more source

BMP4 mutations in tooth agenesis and low bone mass [PDF]

Archives of Oral Biology, 2019
To identify an uncommon genetic cause of tooth agenesis (TA) by utilizing whole exome sequencing (WES) and targeted Sanger sequencing in a cohort of 120 patients with isolated TA.One deleterious mutation in the gene encoding bone morphogenetic protein 4 (BMP4) was identified in 6 unrelated patients with TA by WES.
Miao, Yu, Hao, Wang, Zhuangzhuang, Fan, Chencheng, Xie, Haochen, Liu, Yang, Liu, Dong, Han, Sing-Wai, Wong, Hailan, Feng   +8 more
openaire   +2 more sources

Serum A20 level is associated with bone mineral density in male patients with type 2 diabetes mellitus

Frontiers in Endocrinology
BackgroundA20, also known as TNF-α-induced protein 3 (TNFAIP3), is a crucial negative regulator of inflammation and immune responses. Emerging evidence suggests that A20 is involved in the regulation of glucose metabolism and plays a significant role in ...
Dongxu Han, Dongxu Han, Jingnan Liu, Jingnan Liu, Yu Wang, Yu Wang, Hongxia Wang, Hongxia Wang, Lingdan Yuan, Lingdan Yuan, Wei Jin, Wei Jin, Lige Song, Lige Song   +13 more
doaj   +1 more source

DXA measurements in rett syndrome reveal small bones with low bone mass [PDF]

Journal of Bone and Mineral Research, 2011
Abstract Low bone mass is reported in growth-retarded patients harboring mutations in the X-linked methyl-CpG-binding protein 2 (MECP2) gene causing Rett syndrome (RTT). We present the first study addressing both bone mineral density (BMD) and bone size in RTT.
Roende, Gitte, Ravn, Kirstine, Fuglsang, Kathrine, Andersen, Henrik, Bieber Nielsen, Jytte, Brøndum-Nielsen, Karen, Jensen, Jens-Erik Beck   +6 more
openaire   +3 more sources

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Research progress on the role of cold-sensitive channel TRPM8 in controlling low temperature-induced bone metabolic imbalance

Frigid Zone Medicine, 2023
With increasing aging population, osteoporosis has emerged as a public health problem worldwide. Epidemiological data reveal that the prevalence of osteoporosis in cold regions is high, and low temperatures may crucially affect bone mass.
Zhang Yimeng, Kazakova E. V, Chai Huijuan, Zhou Ping   +3 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Bone turnover and metabolism in patients with early multiple sclerosis and prevalent bone mass deficit: a population-based case-control study. [PDF]

PLoS ONE, 2012
BACKGROUND: Low bone mass is prevalent in ambulatory multiple sclerosis (MS) patients even shortly after clinical onset. The mechanism is not known, but could involve shared etiological risk factors between MS and low bone mass such as hypovitaminosis D ...
Stine Marit Moen, Elisabeth Gulowsen Celius, Leiv Sandvik, Magritt Brustad, Lars Nordsletten, Erik Fink Eriksen, Trygve Holmøy   +6 more
doaj   +1 more source

Relationships among Physical Activity, Pain, and Bone Health in Youth and Adults with Thalassemia: An Observational Study

Thalassemia Reports, 2022
Patients with thalassemia (Thal) engage in less physical activity than non-Thal populations, which may contribute to pain and osteoporosis. The purpose of this study was to assess relationships between physical activity, pain, and low bone mass in a ...
Ellen B. Fung, Elijah K. Goldberg, Sakina Bambot, Raquel Manzo, Ashutosh Lal   +4 more
doaj   +1 more source

Bone health of middle-aged and older surfers [PDF]

, 2019
Purpose: Given the lack of research investigating surfing and bone health, we aimed to assess the bone mineral density (BMD) of middle-aged and older surfers.
Beck, Belinda R., Climstein, Mike, Hing, Wayne A., Pope, Rodney, Rathbone, Evelyne, Simas, Vini   +5 more
core   +1 more source