Results 71 to 80 of about 1,096,019 (304)

Low fat ratio is better riskfFactor than low body mass index for low bone mineral density

Medicine Science, 2017
Osteoporosis is a health problem that limits quality life and may cause morbidity and mortality, unless prevented or actively treated. The objective of the study was to determine the effects of risk factors on bone mineral density. We evaluated 353 women
Fatih Bati
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Genetics of osteoporosis: searching for candidate genes for bone fragility

Archives of Endocrinology and Metabolism
The pathogenesis of osteoporosis, a common disease with great morbidity and mortality, comprises environmental and genetic factors. As with other complex disorders, the genetic basis of osteoporosis has been difficult to identify.
Manuela G. M. Rocha-Braz, Bruno Ferraz-de-Souza   +1 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

The behavior of adaptive bone-remodeling simulation models [PDF]

, 1992
The process of adaptive bone remodeling can be described mathematically and simulated in a computer model, integrated with the finite element method. In the model discussed here, cortical and trabecular bone are described as continuous materials with ...
Beaupré, Beaupré, Bendsoe, Bittner, Carter, Carter, Cowin, Cowin, Cowin, Currey, Frost, Frost, Frost, Fyhrie, Fyhrie, Goldstein, Harrigan, Hart, Hegedus, Hodgskinson, Hollister, Huiskes, Huiskes, Huiskes, Huiskes, Huiskes, Huiskes, Kauffman, Kuiper, Kummer, Mandelbrot, Pauwels, Rice, Roux, Strang, Strang, Verdonschot, Weinans, Weinans, Williams, Wlczek, Wolff, Yates   +42 more
core   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Leptin may play a role in bone microstructural alterations in obese children. [PDF]

, 2014
Bone mass is low and fracture risk is higher in obese children. Hormonal changes in relation to skeletal microstructure and biomechanics have not been studied in obese ...
A. F. Frangi, Boutroy, Burghardt, Burrows, Cao, Child Growth Foundation, Clark, Cole, Cole, Crabtree, D. King, Davidson, Dimitri, Dimitri, Ducy, Engelke, Farooqi, Farr, Farr, Farr, Fornari, Fujita, Goulding, Goulding, Hamrick, J. Walsh, Kalkwarf, Kessler, Khosla, Kontulainen, Lamghari, Leonard, Lorentzon, M. Paggiosi, Manias, Martin, Montague, N. Bishop, Ng, Nishiyama, Nishiyama, Ohwada, P. Dimitri, Paggiosi, Pistoia, R. Eastell, R. M. Jacques, Solomon, Valerio, Vandewalle, Wachter, Wetzsteon, Williams, Yeni, Z. A. Taylor   +54 more
core   +1 more source

Osteoporosis - "a silent killer". A review of the current literature from clinician and physiotherapist perspective

Journal of Education, Health and Sport, 2015
Kocjan Janusz. Osteoporosis - "a silent killer". A review of the current literature from clinician and physiotherapist perspective. Journal of Education, Health and Sport. 2015;5(7):63-70. ISSN 2391-8306.
Janusz Kocjan
doaj   +2 more sources