Results 81 to 90 of about 1,096,019 (304)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Body composition, IGF1 status, and physical functionality in nonagenarians: implications for osteosarcopenia [PDF]

open access: yes, 2018
OBJECTIVES: Body composition alterations occur during aging. The purpose of the present analysis was to explore the functional consequences of the overlap of sarcopenia and osteoporosis, and the potential role of insulin-like growth factor 1 (IGF1) in ...
Cherry, Ke   +7 more
core  

A rare case of Osteogenesis Imperfecta Type III [PDF]

open access: yes, 2014
Osteogenesis imperfecta (OI) the most common genetic cause of osteoporosis is a generalized disorder of connective tissue, characterized by increased bone fragility, low bone mass, recurrent fractures & numerous extra-osseous features with unusual ...
Nagaraj MV, Jehangir HM
core   +1 more source

Correlation of Transferrin Saturation and Serum Ferritin with Bone Mass Density in Adult Transfusion Dependent Beta-Thalassemia Patients

open access: yesJournal of Blood Medicine, 2021
Tubagus Djumhana Atmakusuma,1,2 Jeffry Beta Tenggara2,3 1Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; 2Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia;
Atmakusuma TD, Tenggara JB
doaj  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Influence of exercise and sports on bone

open access: yesJournal of Physical Fitness and Sports Medicine, 2014
In general, exercise and/or sports are effective for bone health. Bone metabolism is influenced by several environmental factors, especially mechanical loading and nutrition.
Naomi Omi
doaj   +1 more source

The Correlation Between Low Body Mass Index (underweight) With Bone Strength On Eldery Women

open access: yesSaintika Medika, 2020
Background : Osteoporosis is a degenerative disease that often happend at women in elderly age with low body mass index. Standard examination for osteoporosis is bone density examination also known as Bone Mineral Density (BMD).
Shafira Dwi Resnasari
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Genetic variation in Wnt/β-catenin and ER signalling pathways in female and male elite dancers and its associations with low bone mineral density: a cross-section and longitudinal study. [PDF]

open access: yes, 2018
The association of genetic polymorphisms with low bone mineral density in elite athletes have not been considered previously. The present study found that bone mass phenotypes in elite and pre-elite dancers are related to genetic variants at the Wnt/β ...
A Guadalupe-Grau   +59 more
core   +2 more sources

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