Results 81 to 90 of about 2,032,538 (389)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Advanced Engineering Materials, EarlyView., 2023 This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng +3 more
wiley +1 more source
Indian Journal of Endocrinology and Metabolism, 2012 Osteoporosis is characterized by reduced bone mass, impaired bone quality, and a propensity to fracture. An "osteoanabolic" should be referred to any therapy that helps increase bone mass. Bone mass represents 80% of bone mechanical strength.
Vishal Gupta +3 more
doaj +1 more source
Bone turnover and metabolism in patients with early multiple sclerosis and prevalent bone mass deficit: a population-based case-control study. [PDF]
PLoS ONE, 2012 BACKGROUND: Low bone mass is prevalent in ambulatory multiple sclerosis (MS) patients even shortly after clinical onset. The mechanism is not known, but could involve shared etiological risk factors between MS and low bone mass such as hypovitaminosis D ...
Stine Marit Moen +6 more
doaj +1 more source
Determination of bone mineral mass in vivo [PDF]
, 1975 Radiographic equipment incorporates two radiation sources, generating high-energy and low-energy beams. Recording equipment measures amount of radiation that has penetrated limb.
Cameron, J. R., Judy, P. F.
core +1 more source
Recent origin of low trabecular bone density in modern humans [PDF]
, 2014 Humans are unique, compared with our closest living relatives (chimpanzees) and early fossil hominins, in having an enlarged body size and lower limb joint surfaces in combination with a relatively gracile skeleton (i.e., lower bone mass for our body ...
Bernhard Zipfel +11 more
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner. [PDF]
PLoS ONE, 2009 We investigated the role of Lef1, one of the four transcription factors that transmit Wnt signaling to the genome, in the regulation of bone mass. Microcomputed tomographic analysis of 13- and 17-week-old mice revealed significantly reduced trabecular ...
Tommy Noh +18 more
doaj +1 more source
Lumbar Bone Mass Predicts Low Back Pain in Males [PDF]
Spine, 2012 Longitudinal study of lumbar bone mass as predictor of low back pain (LBP).To investigate whether low bone mineral content (BMC) and bone mineral density (BMD) values at the age of 36 years are associated with the prevalence of LBP at the age of 42 years among the study population of the Amsterdam Growth and Health Longitudinal Study.Results of ...
Hoozemans, M.J.M. +3 more
openaire +4 more sources
Bone mineral density in Iranian patients: Effects of age, sex, and body mass index [PDF]
, 2013 Introduction: Osteoporosis is a multifactorial skeletal disease that is characterized by reduced bone mineral density (BMD). BMD values de-pend on several factors such as age, sex and age at menopause.
Aghaei, M. +4 more
core +1 more source