Results 31 to 40 of about 100,458 (262)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

An adaptive neuro-fuzzy inference system for forecasting australia’s domestic low cost carrier passenger demand

Aviation, 2015
This study has proposed and empirically tested two Adaptive Neuro-Fuzzy Inference System (ANFIS) models for the first time for predicting Australia‘s domestic low cost carriers‘ demand, as measured by enplaned passengers (PAX Model) and revenue passenger
Panarat Srisaeng, Glenn S. Baxter, Graham Wild   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Forecasting Australia’s domestic low cost carrier passenger demand using a genetic algorithm approach

Aviation, 2016
This study has proposed and empirically tested for the first time Genetic Algorithm (GA) models for forecasting Australia’s domestic low cost carriers’ demand, as measured by enplaned passengers (GAPAXDE Model) and revenue passenger kilometres performed (
Panarat Srisaeng, Steven Richardson, Glenn S. Baxter, Graham Wild   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Do regional airlines in Eastern Europe have the right to survive in the European single sky environment?

Aviation, 2017
The European aviation market can be characterised by extreme growth and turbulence ever since the markets were deregulated and low cost carriers emerged on the continent.
Sven Kukemelk
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Is Physical Evidence Still Valid? A Study of Low Cost Carriers in Indonesia

Gadjah Mada International Journal of Business, 2015
Physical evidence has been widely accepted as variable that has impact on satisfaction, specifically in airline service. However, this study showed some opposite result for low cost airlines in Indonesia.
Yasintha Soelasih
doaj   +1 more source

Low-Cost Carriers and Airports: A Complex Relationship [PDF]

, 2017
In the last decades, low-cost carriers have generated several changes in the air market for both passengers and airports. Mainly for regional airports, low-cost carriers have represented an important opportunity to improve their connectivity levels and passenger traffic.
P. Beria, LAURINO, ANTONIO, M. N. Postorino   +2 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source