Results 11 to 20 of about 1,515,008 (404)

Small Dense Low‐Density Lipoprotein Cholesterol Is the Most Atherogenic Lipoprotein Parameter in the Prospective Framingham Offspring Study

Journal of the American Heart Association, 2021
Background Elevated plasma levels of direct low‐density lipoprotein cholesterol (LDL‐C), small dense LDL‐C (sdLDL‐C), low‐density lipoprotein (LDL) triglycerides, triglycerides, triglyceride‐rich lipoprotein cholesterol, remnant lipoprotein particle ...
Hiroaki Ikezaki, Elise Lim, L Adrienne Cupples   +2 more
exaly   +2 more sources

Low-density lipoprotein particles in atherosclerosis

Frontiers in Physiology, 2022
Among the diseases causing human death, cardiovascular disease (CVD) remains number one according to the World Health Organization report in 2021. It is known that atherosclerosis is the pathological basis of CVD.
Ya-Nan Qiao, Yan-Li Zou, Shou-Dong Guo
doaj   +2 more sources

Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)

Pharmaceuticals, 2023
Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e.,
Niki Katsiki, Michal Vrablik, Maciej Banach, Ioanna Gouni-Berthold   +3 more
doaj   +3 more sources

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

Clinical Chemistry, 1972
Robert I Levy, Donald S Fredrickson, Fredrickson Donald S   +2 more
exaly   +2 more sources

Emerging low-density lipoprotein therapies: Targeting PCSK9 for low-density lipoprotein reduction [PDF]

Journal of Clinical Lipidology, 2013
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protein secreted by the hepatocyte that regulates the surface expression of low-density lipoprotein (LDL) receptors by targeting them for lysosomal degradation. Statins enhance PCSK9 synthesis, an effect that blunts the LDL-cholesterol (-C)-lowering effectiveness of statins.
Michael H. Davidson
openalex   +3 more sources

Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk

Vascular Health and Risk Management, 2009
Rakesh K Sharma1, Vibhuti N Singh2, Hanumanth K Reddy11Medical Center of South Arkansas, El Dorado, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Bayfront Medical Center, University of South Florida, St. Petersburg, FL, USAAbstract:
Rakesh K Sharma, Vibhuti N Singh, Hanumanth K Reddy   +2 more
doaj   +1 more source

Physiological Bases for the Superiority of Apolipoprotein B Over Low‐Density Lipoprotein Cholesterol and Non–High‐Density Lipoprotein Cholesterol as a Marker of Cardiovascular Risk

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
In 2019, the European Society of Cardiology/European Atherosclerosis Society stated that apolipoprotein B (apoB) was a more accurate marker of cardiovascular risk than low‐density lipoprotein cholesterol (LDL‐C) and non–high‐density lipoprotein ...
Tamara Glavinovic, G. Thanassoulis, J. de Graaf, P. Couture, R. Hegele, A. Sniderman   +5 more
semanticscholar   +1 more source

Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease

Cells, 2023
Alterations in lipid composition and disturbed lipoprotein metabolism are involved in the pathomechanism of Huntington’s disease (HD). Here, we measured 112 lipoprotein subfractions and components in the plasma of 20 normal controls, 24 symptomatic ...
Kuo-Hsuan Chang, Mei-Ling Cheng, Chi-Jen Lo, Chun-Ming Fan, Yih-Ru Wu, Chiung-Mei Chen   +5 more
doaj   +1 more source

N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors

International Journal of Nanomedicine, 2014
Chun-ge Zhang,*,1 Qiao-ling Zhu,*,1 Yi Zhou,*,1,2 Yang Liu,1 Wei-liang Chen,1 Zhi-Qiang Yuan,1 Shu-di Yang,1 Xiao-feng Zhou,3,4 Ai-jun Zhu,1 Xue-nong Zhang,*,1 Yong Jin*,5 1Department of Pharmaceutics, College of Pharmaceutical Sciences, Soochow ...
Zhang CG, Zhu QL, Zhou Y, Liu Y, Chen WL, Yuan ZQ, Yang SD, Zhou XF, Zhu AJ, Zhang XN, Jin Y   +10 more
doaj   +1 more source

A New Equation for Calculation of Low-Density Lipoprotein Cholesterol in Patients With Normolipidemia and/or Hypertriglyceridemia.

JAMA cardiology, 2020
Importance Low-density lipoprotein cholesterol (LDL-C), a key cardiovascular disease marker, is often estimated by the Friedewald or Martin equation, but calculating LDL-C is less accurate in patients with a low LDL-C level or hypertriglyceridemia ...
M. Sampson, Clarence Ling, Qian Sun, Roa Harb, M. Ashmaig, R. Warnick, A. Sethi, James K. Fleming, J. Otvos, J. Meeusen, S. Delaney, A. Jaffe, R. Shamburek, M. Amar, A. Remaley   +14 more
semanticscholar   +1 more source