Results 21 to 30 of about 10,449,342 (203)

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]

Journal of Lipid Research, 2014
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger, Markus Heine, Roshni Singaraja, Michael Hayden, May Brundert, Rajasekhar Ramakrishnan, Joerg Heeren   +6 more
doaj   +1 more source

Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S]

Journal of Lipid Research, 2014
Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role.
Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul   +5 more
doaj   +1 more source

The effect of eight weeks of 30-20-10 interval training on serum spexin levels and lipid profile in obese middle-aged men [PDF]

فیزیولوژی ورزش و فعالیت بدنی, 2023
Background and Purpose: The purpose of this study was to investigate the effect of 30-20-10 interval training on the serum spexin level and lipid profile of obese men in order to measure the effect of physical activity on increasing spexin and improving ...
Hamid Yazdanshenas, Roghayeh Fakhrpour, Bahloul Ghorbanian   +2 more
doaj   +1 more source

Combined data from LDL composition and size measurement are compatible with a discoid particle shape

Journal of Lipid Research, 2004
The size of LDL is usually reported as particle diameter, with the implicit assumption that it is a spherical particle. On the other hand, data obtained by cryoelectron microscopy and crystallographic analysis suggest that LDL shape may be discoid.
Tom Teerlink, Peter G. Scheffer, Stephan J.L. Bakker, Robert J. Heine   +3 more
doaj   +1 more source

1H NMR spectroscopy quantifies visibility of lipoproteins, subclasses, and lipids at varied temperatures and pressures

Journal of Lipid Research, 2019
NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the absolute NMR ...
Daniela Baumstark, Werner Kremer, Alfred Boettcher, Christina Schreier, Paul Sander, Gerd Schmitz, Renate Kirchhoefer, Fritz Huber, Hans Robert Kalbitzer   +8 more
doaj   +1 more source

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

Journal of Lipid Research, 2005
Apolipoprotein E (apoE) associates with lipoproteins and mediates their interaction with members of the LDL receptor family. ApoE exists as three common isoforms that have important distinct functional and biological properties.
Jose Ruiz, Diana Kouiavskaia, Molly Migliorini, Susan Robinson, Evgueni L. Saenko, Natalia Gorlatova, Donghua Li, Daniel Lawrence, Bradley T. Hyman, Karl H. Weisgraber, Dudley K. Strickland   +10 more
doaj   +1 more source

Effect of Poloxamer 407 on serum VLDL, LDL and HDL levels of rabbits

National Journal of Physiology, Pharmacy and Pharmacology, 2014
Background: Poloxamer 407 is used in parenteral formulations as solubilizing and wetting agent for traditional, low-molecular-weight organic drug molecules and as stabilizing agent for proteins and polypeptide drugs.
Harish Govind Naik, Ashwini Kolur, Dundesh Maled, Chitra C Khanwelkar, Rohit Desai, Sunil Gidamudi   +5 more
doaj   +1 more source

The inconspicuous health benefit of blood donation

Global Journal of Transfusion Medicine, 2020
Background and Objectives: Regular blood donations seem to be beneficial to the health of donors in many ways. There is evidence to suggest that blood donation lowers blood viscosity and alters lipid profile, which is an acceptable parameter for ...
Alhaji Bukar, Erhabor Amos Tosan, Osita Simon Obi, Ajibola Sikiru Akinola, Gimba Waziri, Medugu Jessy Thomas, Aghatise Kevin, Christy Chinyere Fredrick, Osareniro Eguagie Osakue, Geogina Erifeta, Humphrey B Osadolor, Mathew Folaranmi Olaniyan   +11 more
doaj   +1 more source

Lipoprotein separation in a novel iodixanol density gradient, for composition, density, and phenotype analysis

Journal of Lipid Research, 2008
Separation of lipoproteins by traditional sequential salt density floatation is a prolonged process (∼72 h) with variable recovery, whereas iodixanol-based, self-generating density gradients provide a rapid (∼4 h) alternative.
Michael S. Yee, Darrell V. Pavitt, Tira Tan, Soundararajan Venkatesan, Ian F. Godsland, William Richmond, Desmond G. Johnston   +6 more
doaj   +1 more source