Results 21 to 30 of about 585,583 (302)

The inconspicuous health benefit of blood donation

Global Journal of Transfusion Medicine, 2020
Background and Objectives: Regular blood donations seem to be beneficial to the health of donors in many ways. There is evidence to suggest that blood donation lowers blood viscosity and alters lipid profile, which is an acceptable parameter for ...
Alhaji Bukar, Erhabor Amos Tosan, Osita Simon Obi, Ajibola Sikiru Akinola, Gimba Waziri, Medugu Jessy Thomas, Aghatise Kevin, Christy Chinyere Fredrick, Osareniro Eguagie Osakue, Geogina Erifeta, Humphrey B Osadolor, Mathew Folaranmi Olaniyan   +11 more
doaj   +1 more source

Lipoprotein separation in a novel iodixanol density gradient, for composition, density, and phenotype analysis

Journal of Lipid Research, 2008
Separation of lipoproteins by traditional sequential salt density floatation is a prolonged process (∼72 h) with variable recovery, whereas iodixanol-based, self-generating density gradients provide a rapid (∼4 h) alternative.
Michael S. Yee, Darrell V. Pavitt, Tira Tan, Soundararajan Venkatesan, Ian F. Godsland, William Richmond, Desmond G. Johnston   +6 more
doaj   +1 more source

Low-density lipoprotein particles in atherosclerosis

Frontiers in Physiology, 2022
Among the diseases causing human death, cardiovascular disease (CVD) remains number one according to the World Health Organization report in 2021. It is known that atherosclerosis is the pathological basis of CVD.
Ya-Nan Qiao, Yan-Li Zou, Shou-Dong Guo
doaj   +1 more source

Metabolic origins and clinical significance of LDL heterogeneity

Journal of Lipid Research, 2002
LDLs in humans comprise multiple distinct subspecies that differ in their metabolic behavior and pathologic roles. Metabolic turnover studies suggest that this heterogeneity results from multiple pathways, including catabolism of different VLDL and IDL ...
Kaspar K. Berneis, Ronald M. Krauss
doaj   +1 more source

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. [PDF]

, 2018
Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324 participants from four ancestries at mean depth >29X and analyze genotypes with four quantitative ...
Abecasis, Goncalo, Alver, Maris, Bloom, Jonathan M, Chaffin, Mark, Correa, Adolfo, Cupples, L Adrienne, Engreitz, Jesse M, Ernst, Jason, Esko, Tonu, Ganna, Andrea, Johnson, W Craig, Kathiresan, Sekar, Kellis, Manolis, Khera, Amit V, Lander, Eric S, Manichaikul, Ani, Mitchell, Braxton, Montasser, May, Natarajan, Pradeep, Neale, Benjamin M, NHLBI TOPMed Lipids Working Group, O'Connell, Jeffrey R, Peloso, Gina M, Perry, James A, Poterba, Timothy, Rich, Stephen S, Ripatti, Samuli, Rotter, Jerome I, Ruotsalainen, Sanni E, Salomaa, Veikko, Seed, Cotton, Surakka, Ida L, Vasan, Ramachandran S, Willer, Cristen J, Wilson, James G, Zekavat, Seyedeh Maryam, Zhou, Wei   +36 more
core   +2 more sources

Low-Density Lipoproteins Oxidation and Endometriosis [PDF]

Mediators of Inflammation, 2013
The etiopathogenesis of endometriosis still remains unknown. Recent data provide new valuable information concerning the role of oxidative stress in the pathophysiology of the disease. It has been proved that levels of different lipid peroxidation end products are increased in both peritoneal fluid (PF) and serum of endometriotic patients.
Grzegorz Polak, Bartłomiej Barczyński, Wojciech Kwaśniewski, Wiesława Bednarek, Iwona Wertel, Magdalena Derewianka-Polak, Jan Kotarski   +6 more
openaire   +3 more sources

The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis[S]

Journal of Lipid Research, 2015
Perlecan is a major heparan sulfate (HS) proteoglycan in the arterial wall. Previous studies have linked it to atherosclerosis. Perlecan contains a core protein and three HS side chains. Its core protein has five domains (DI–DV) with disparate structures
Yu-Xin Xu, David Ashline, Li Liu, Carlos Tassa, Stanley Y. Shaw, Katya Ravid, Matthew D. Layne, Vernon Reinhold, Phillips W. Robbins   +8 more
doaj   +1 more source

Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]

, 2013
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A., Caslake, M.J., Cooney, J., Freeman, D.J., Griffin, B.A., Meyer, B.J., Nilsson, S., Olivecrona, G., Ramsay, J.E., Stewart, F.M.   +9 more
core   +2 more sources

Low-Density Lipoprotein Receptors

, 1991
The origins of the receptor theory are based on the work of Paul Ehrlich (1854–1915) and John Newport Langley (1852–1925) (Parascandola 1981), who were the first to postulate that specific cellular reactions to drugs must be based on so-called receptive substances.
Niendorf, A., Beisiegel, Ulrike, Seifert, G.   +2 more
openaire   +3 more sources

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice [PDF]

, 2006
OBJECTIVE - The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a ...
Dallinga-Thie, G.M. (Geesje), Haan, W. (Willeke) de, Havekes, L.M. (Louis), Hoogt, C.C. (Caroline) van der, Jukema, J.W. (Jan Wouter), Offerman, E. (Erik), Rensen, P.C.N. (Patrick), Westerterp, M. (Marit)   +7 more
core   +5 more sources