Results 21 to 30 of about 1,515,008 (404)

Mechanistic Insights into the Oxidized Low-Density Lipoprotein-Induced Atherosclerosis

Oxidative Medicine and Cellular Longevity, 2020
Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of medium to large arteries. Atherosclerosis is the prime root of cardiovascular events contributing to the most considerable number of morbidity and mortality ...
Chainika Khatana, N. Saini, S. Chakrabarti, V. Saini, A. Sharma, R. Saini, A. Saini   +6 more
semanticscholar   +1 more source

Relationship between Renal Function, Fibrin Clot Properties and Lipoproteins in Anticoagulated Patients with Atrial Fibrillation

Biomedicines, 2022
Background: Mechanisms by which chronic kidney disease (CKD) influences fibrin clot properties in atrial fibrillation (AF) remain ill-defined. We aimed to investigate the effects of AF and CKD on fibrin clot properties and lipoproteins, and determine the
Wern Yew Ding, Ian G. Davies, Dhiraj Gupta, Gregory Y. H. Lip   +3 more
doaj   +1 more source

Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9

Journal of Lipid Research, 2008
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has gained attention as a key regulator of serum low density lipoprotein cholesterol (LDL-C) levels. This novel protease causes the degradation of hepatic low density lipoprotein receptors. In humans,
Holly E. Careskey, R. Aleks Davis, William E. Alborn, Jason S. Troutt, Guoqing Cao, Robert J. Konrad   +5 more
doaj   +1 more source

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, Panovska, J., Byrne, H.M., Jackson, K.G., H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Wattis, J.A.D., Pickersgill, L, Pickersgill, L., Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, O'Malley, B., Blackburn, H., Jackson, KG, J. Panovska   +22 more
core   +1 more source

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

Journal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry, T Olivecrona, R J Deckelbaum, S Eisenberg   +3 more
doaj   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

Low-Density Lipoproteins Oxidation and Endometriosis [PDF]

Mediators of Inflammation, 2013
The etiopathogenesis of endometriosis still remains unknown. Recent data provide new valuable information concerning the role of oxidative stress in the pathophysiology of the disease. It has been proved that levels of different lipid peroxidation end products are increased in both peritoneal fluid (PF) and serum of endometriotic patients.
Grzegorz Polak, Bartłomiej Barczyński, Wojciech Kwaśniewski, Wiesława Bednarek, Iwona Wertel, Magdalena Derewianka-Polak, Jan Kotarski   +6 more
openaire   +3 more sources

High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]

Journal of Lipid Research, 2014
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger, Markus Heine, Roshni Singaraja, Michael Hayden, May Brundert, Rajasekhar Ramakrishnan, Joerg Heeren   +6 more
doaj   +1 more source

The effect of eight weeks of 30-20-10 interval training on serum spexin levels and lipid profile in obese middle-aged men [PDF]

فیزیولوژی ورزش و فعالیت بدنی, 2023
Background and Purpose: The purpose of this study was to investigate the effect of 30-20-10 interval training on the serum spexin level and lipid profile of obese men in order to measure the effect of physical activity on increasing spexin and improving ...
Hamid Yazdanshenas, Roghayeh Fakhrpour, Bahloul Ghorbanian   +2 more
doaj   +1 more source

Oxidized Low-Density Lipoprotein [PDF]

, 2009
Oxidized low-density lipoprotein (Ox-LDL) has been studied for over 25 years. Numerous pro- and anti-atherogenic properties have been attributed to Ox-LDL. Yet, Ox-LDL has neither been defined nor characterized, as its components and composition change depending on its source, method of preparation, storage, and use. It contains unoxidized and oxidized
Sampath, Parthasarathy, Achuthan, Raghavamenon, Mahdi Omar, Garelnabi, Nalini, Santanam   +3 more
openaire   +2 more sources