Results 261 to 270 of about 585,583 (302)

The low density lipoprotein receptor

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989
The study of familial hypercholesterolemia at the molecular level has led to its advancement from a clinical syndrome to a fascinating experimental system. FH was first described 50 years ago by Carl Müller who concluded that the disease produces high plasma cholesterol levels and myocardial infarctions in young people, and is transmitted as an ...
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High-density lipoprotein, low-density lipoprotein and coronary artery disease

The American Journal of Cardiology, 1990
Lipoprotein cholesterol data from the Framingham Heart Study show that low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels are important in determining risk for coronary artery disease (CAD). Increased LDL and decreased HDL cholesterol levels are associated with an increase in CAD.
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Low-Density Lipoprotein Density and Atherosclerosis

JAMA, 1994
To provide an overview of the relationship between low-density lipoprotein (LDL) density and coronary artery disease and to examine this relationship in terms of lipid peroxidation and the atherogenic remnant hypothesis.English-language studies and reviews pertaining to LDL composition and size were identified through a MEDLINE search and reference ...
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Low-density Lipoproteins in Atherogenesis

2000
It is well established that high levels of plasma cholesterol, particularly those associated with low-density lipoprotein (LDL), increase the risk of developing atherosclerosis. It is also clear that lowering plasma cholesterol levels can arrest or even reverse the progression of the disease [1,2].
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Low Density Lipoprotein Apheresis

2013
Therapeutic plasma exchange volume is usually 3–5 L/session. Removal of positively charged particles as well as low density lipoprotein cholesterol improves focal segmental glomerulosclerosis and peripheral arterial disease. Angiotensin converting enzyme (ACE) inhibitors should be discontinued at least 2–3 days prior to low density ...
Kenjiro Honda, Kent Doi
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[Modified low-density lipoprotein].

Nihon rinsho. Japanese journal of clinical medicine, 1995
Oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of coronary artery disease (CAD). Macrophages take up oxidized LDL via scavenger receptors, which is not regulated by cellular cholesterol contents, and oxidized LDL stimulates cholesterol esterification and this results in cellular cholesterol accumulation ...
H, Yoshida, H, Nakamura
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Mammalian Low Density Lipoproteins

1976
During the past few years considerable advances have been made in the study of mammalian plasma low density lipoproteins. Although human LDL is of prime interest, mainly because of its association with atherosclerosis, many studies can most satisfactorily be carried out on animals, including work on the mechanisms of LDL production and metabolism, the ...
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Oxidised Low Density Lipoproteins

1993
The evidence for the oxidative modification of low density lipoprotein (LDL) and its subsequent recognition by the scavenger receptors on macrophages in vitro is clear. The presence of oxidatively modified LDL in atherosclerotic lesions is well-recognised. However, the mechanism whereby LDL becomes oxidised in vivo is yet to be clarified.
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Lipoprotein Metabolism: Chylomicrons, Very-Low-Density Lipoproteins and Low-Density Lipoproteins

2015
Verne Schumaker, Audra Lembertas
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Low Density Lipoproteins

Biochemical Society Transactions, 1978
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