Results 251 to 260 of about 1,515,008 (404)

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects.

New England Journal of Medicine, 1990
R. Mensink, M. Katan
semanticscholar   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Aminoguanidine inhibits oxidative modification of low density lipoprotein protein and the subsequent increase in uptake by macrophage scavenger receptors.

, 1992
Sylvie Picard, Srinivasan Parthasarathy, Joachim Fruebis, Joseph L. Witztum   +3 more
openalex   +1 more source

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

Journal of Clinical Investigation, 1993
S. Ishibashi, Michael S. Brown, J. Goldstein, R. Gerard, R. Hammer, J. Herz   +5 more
semanticscholar   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Epidemiological characteristics of serum small dense low-density lipoprotein cholesterol: From 2017 to 2019 in Chengdu adults, China. [PDF]

Medicine (Baltimore)
Li J, Lv Z, He E, Wang H, Wu L, Wei Y, Quan H, Zhang S.   +7 more
europepmc   +1 more source

An apo-E-free very low density lipoprotein enriched in phosphatidylethanolamine in human plasma.

, 1986
P E Fielding, C J Fielding
openalex   +1 more source

Abnormal low density plasma lipoproteins occurring in dogs with obstructive jaundice [PDF]

, 1976
Bengt Danielsson, Rolf Ekman, Bengt G. Johansson, Bengt G. Petersson   +3 more
openalex   +1 more source

Role of oxidized low density lipoprotein in atherogenesis.

Journal of Clinical Investigation, 1991
J. Witztum, D. Steinberg
semanticscholar   +1 more source