Results 251 to 260 of about 585,583 (302)

Electronegative low-density lipoprotein

Current Opinion in Lipidology, 2004
The occurrence in blood of an electronegatively charged LDL was described in 1988. During the 1990s reports studying electronegative LDL (LDL(-)) were scant and its atherogenic role controversial. Nevertheless, recent reports have provided new evidence on a putative atherogenic role of LDL(-).
José Luis, Sánchez-Quesada, Sonia, Benítez, Jordi, Ordóñez-Llanos   +2 more
openaire   +2 more sources

Low-density lipoprotein heterogeneity

Baillière's Clinical Endocrinology and Metabolism, 1995
As a key feature of the ALP, a raised level of small, dense LDL forms part of what is potentially the most common collection of lipoprotein abnormalities to influence the risk of CHD in the general population. The consistency of the association between a prevalence of small, dense LDL and increased risk of CHD is impressive, though the practical ...
openaire   +2 more sources

Circulating low density lipoprotein (LDL)

Hormone Molecular Biology and Clinical Investigation, 2018
Abstract Low-density lipoprotein (LDL) particles are known as atherogenic agents in coronary artery diseases. They modify to other electronegative forms and may be the subject for improvement of inflammatory events in vessel subendothelial spaces. The circulating LDL value is associated with the plasma PCSK-9 level. They internalize into
Mohsen, Khosravi, Reza, Hosseini-Fard, Mohammad, Najafi   +2 more
openaire   +2 more sources

Evaluation of Malondialdehyde Low-Density Lipoprotein Stratified by Low-Density Lipoprotein Cholesterol

Clinical Laboratory, 2017
Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited.This study included 778 Japanese subjects who were not taking ...
Kengo, Moriyama, Eiko, Takahashi
openaire   +2 more sources

Modified Low-Density Lipoproteins and High-Density Lipoproteins

Pathophysiology of Haemostasis and Thrombosis, 2006
It has long been known that the oxidative state of the various plasma lipoproteins modulates platelet aggregability, thereby contributing to atherogenesis. Low-density lipoprotein (LDL), occurring in vivo both in the native and oxidised forms, interacts directly with platelets, by binding to specific receptors.
Elisabeth Koller, Ivo Volf, Aner Gurvitz, Franz Koller   +3 more
openaire   +1 more source

Low-density lipoprotein oxidation.

Italian heart journal : official journal of the Italian Federation of Cardiology, 2001
Free radical mediated oxidation of low-density lipoproteins (LDL), which has been extensively studied in the last two decades, plays a central role in the development of the atherosclerotic plaque. Oxidation involves the lipid moiety of LDL in a chain reaction mechanism.
IULIANO, Luigi, MICHELETTA F, VIOLI, Francesco   +2 more
openaire   +2 more sources

Platelet Activation by Low Density Lipoprotein and High Density Lipoprotein

Pathophysiology of Haemostasis and Thrombosis, 2006
Cardiovascular disease is the main cause of death and disability in the Western society. Lipoproteins are important in the development of cardiovascular disease since they change the properties of different cells involved in atherosclerosis and thrombosis. The interaction of platelets with lipoproteins has been under intense investigation. Particularly
Suzanne J A, Korporaal, Jan-Willem N, Akkerman   +1 more
openaire   +2 more sources

Low-density lipoprotein binding assay using the calf adrenocortical low-density lipoprotein receptor

Clinical Biochemistry, 1994
The low-density lipoprotein (LDL) receptor was purified to a semipure solubilized form from calf adrenocortical tissue. This receptor was found to be a suitable substitute for the human LDL receptor for studying human LDL binding. The apparent dissociation constant of the receptor from calf adrenocortical cells, using human LDL as the ligand, was found
P, Catomeris, R J, Thibert, T F, Draisey
openaire   +2 more sources

Low Density Lipoproteins and Hypercholesterolemia

1989
Coronary and vascular disease of atherosclerotic origin are the main causes of death and at the same time the most frequent reasons for early invalidity in the Federal Republic of Germany and other industrialized nations. In particular, coronary heart disease (CHD) is the major cause of death in middle-aged men.
G, Assmann, H, Funke, G, Schmitz
openaire   +2 more sources