Results 301 to 310 of about 784,891 (338)

High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990
Oxidatively modified low-density lipoprotein (LDL), generated as a result of incubation of LDL with specific cells (e.g., endothelial cells, EC) or redox metals like copper, has been suggested to be an atherogenic form of LDL. Epidemiological evidence suggests that higher concentrations of plasma high-density lipoprotein (HDL) are protective against ...
Sampath Parthasarathy, Joellen Barnett, Loren G. Fong   +2 more
openaire   +3 more sources

Receptors for modified low-density lipoproteins on human endothelial cells: different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1991
We examined the uptake pathway of acetylated low-density lipoprotein and oxidatively modified LDL (oxidized LDL) in human umbilical vein endothelial cells in culture. Proteolytic degradation of 125I-labeled Ac-LDL or Ox-LDL in the confluent monolayer of human endothelial cells was time-dependent and showed saturation kinetics in the dose-response ...
Hidenori Arai, Noriaki Kume, Chuichi Kawai, Toru Kita   +3 more
openaire   +3 more sources

Immunity to Low-Density Lipoprotein [PDF]

, 2011
Animal experiments, epidemiological studies and clinical investigations all show that high levels of plasma low-density lipoprotein (LDL) promote atherosclerotic cardiovascular disease [1]. LDL particles contain epitopes that trigger cellular and humoral immune responses. Autoimmunization during the course of atherosclerosis generates proinflammatory T
Göran K. Hansson, Göran K. Hansson
openaire   +1 more source

Low-density lipoprotein oxidation.

Italian heart journal : official journal of the Italian Federation of Cardiology, 2001
Free radical mediated oxidation of low-density lipoproteins (LDL), which has been extensively studied in the last two decades, plays a central role in the development of the atherosclerotic plaque. Oxidation involves the lipid moiety of LDL in a chain reaction mechanism.
IULIANO, Luigi, MICHELETTA F, VIOLI, Francesco   +2 more
openaire   +2 more sources

Atherosclerosis regression: Is low-density lipoprotein or high-density lipoprotein the answer?

Current Atherosclerosis Reports, 2007
Lowering low-density lipoprotein cholesterol is the cornerstone of risk modification in patients with established coronary artery disease. Considerable attention is currently focused on developing pharmacologic agents that promote the biologic activity of high-density lipoprotein.
Steven E. Nissen, Stephen J. Nicholls, E. Murat Tuzcu   +2 more
openaire   +3 more sources

High-density lipoprotein, low-density lipoprotein and coronary artery disease

The American Journal of Cardiology, 1990
Lipoprotein cholesterol data from the Framingham Heart Study show that low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels are important in determining risk for coronary artery disease (CAD). Increased LDL and decreased HDL cholesterol levels are associated with an increase in CAD.
openaire   +3 more sources

Lipoprotein Metabolism: Chylomicrons, Very-Low-Density Lipoproteins and Low-Density Lipoproteins [PDF]

, 2015
Audra V. Lembertas, Verne N. Schumaker
openaire   +1 more source

Low Density Lipoproteins [PDF]

Biochemical Society Transactions, 1978
openaire   +1 more source

Low Density Lipoprotein Apheresis

2013
Therapeutic plasma exchange volume is usually 3–5 L/session. Removal of positively charged particles as well as low density lipoprotein cholesterol improves focal segmental glomerulosclerosis and peripheral arterial disease. Angiotensin converting enzyme (ACE) inhibitors should be discontinued at least 2–3 days prior to low density ...
Kent Doi, Kenjiro Honda
openaire   +2 more sources

Low density lipoprotein

2018
D. Peetz, K. J. Lackner
openaire   +2 more sources