Results 51 to 60 of about 1,515,008 (404)

Italian Multicenter Study on Low-Density Lipoprotein Apheresis Working Group 2009 Survey

open access: yes, 2013
We present results of the second survey of the Italian Multicenter Study on Low-Density Lipoprotein Apheresis (IMSLDLa-WG/2). The study involved 18 centers in 2009, treating 66 males and 35 females, mean age 47 +/- 18 years.
MOROZZI, CLAUDIA   +3 more
core   +1 more source

Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low‐Density Lipoprotein Cholesterol

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Levels of LDL (low‐density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual lipid‐related pathways of atherosclerotic cardiovascular disease risk beyond LDL cholesterol.
P. Lawler   +10 more
semanticscholar   +1 more source

LDL and HDL transfer rates across peripheral microvascular endothelium agree with those predicted for passive ultrafiltration in humans

open access: yesJournal of Lipid Research, 2015
The mechanisms by which LDLs and HDLs cross the vascular endothelium from plasma into interstitial fluid are not understood, and have never been studied in humans in vivo.
C. Charles Michel   +3 more
doaj   +1 more source

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

open access: yesNature Genetics, 2008
Blood concentrations of lipoproteins and lipids are heritable risk factors for cardiovascular disease. Using genome-wide association data from three studies (n = 8,816 that included 2,758 individuals from the Diabetes Genetics Initiative specific to the ...
S. Kathiresan   +29 more
semanticscholar   +1 more source

Metabolic heterogeneity in the formation of low density lipoprotein from very low density lipoprotein in the rat: evidence for the independent production of a low density lipoprotein subfraction.

open access: yesJournal of Lipid Research, 1978
The formation of low density lipoprotein (LDL) from very low density lipoprotein (VLDL) was studied after injecting 14C-radiomethylated or 125I-radioiodinated VLDL into rats.
N H Fidge, P Poulis
doaj   +1 more source

Changes in the Plasma Lipid Profile as a Potential Predictor of Clinical Outcome in Dengue Hemorrhagic Fever [PDF]

open access: yes, 2002
In 50 consecutive children admitted to the intensive care unit with the clinical diagnosis of dengue hemorrhagic fever (DHF)/dengue shock syndrome (grade III or IV), 20 patients with mild DHF (grade I or II), and 20 healthy control patients, the plasma ...
Suharti, C.   +16 more
core   +1 more source

Low-density lipoprotein mimics blood plasma-derived exosomes and microvesicles during isolation and detection

open access: yesScientific Reports, 2016
Circulating extracellular vesicles have emerged as potential new biomarkers in a wide variety of diseases. Despite the increasing interest, their isolation and purification from body fluids remains challenging.
Barbara W. Sódar   +17 more
semanticscholar   +1 more source

Non-oxidative modification of native low-density lipoprotein by oxidized low-density lipoprotein [PDF]

open access: yesBiochemical Journal, 1996
The oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of atherosclerosis, although little is known as yet about the precise mechanism of oxidation in vivo. The studies presented here demonstrate that, in the absence of cells or transition metals, oxidized LDL can modify native LDL through co-incubation in ...
M, Yang, D S, Leake, C A, Rice-Evans
openaire   +2 more sources

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

open access: yes, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source

Low Density Lipoprotein Oxidation and Its Pathobiological Significance*

open access: yesJournal of Biological Chemistry, 1997
Background The fact that low density lipoprotein (LDL) 1 is extremely sus- ceptible to oxidative damage has been known for some time (1, 2), but until quite recently this was primarily a nuisance for the student of lipoprotein metabolism.
D. Steinberg
semanticscholar   +1 more source

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