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Alirocumab for low-density Lipoprotein Cholesterol Lowering
Future Cardiology, 2018Ischemic heart disease and stroke are the leading causes of death in the world currently. Both of these conditions are primarily caused by atherosclerosis, the underlying pathophysiology of which is the deposition of lipid, specifically low-density lipoprotein cholesterol (LDL-C) within the arterial bed. PCSK9, is a proteolytic enzyme, which indirectly
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Lipoprotein(a) Cholesterol Masquerading as Low-Density Lipoprotein Cholesterol
Journal of the American College of Cardiology, 2022Guillaume Paré +2 more
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Beyond Low-Density Lipoprotein Cholesterol
Archives of Internal Medicine, 1996Evidence supports the involvement of 2 common dyslipidemias---low high-density lipoprotein disorders and Lp(a) lipoprotein excess--in coronary heart disease. Until clinical trials determine whether specific therapeutic interventions can prevent the occurrence and recurrence of coronary heart disease in patients with these dyslipidemias, the ...
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Metabolism, 2005
To investigate some individual and genetic factors that may influence the response of low-density lipoprotein cholesterol (LDL-C) to pravastatin treatment, we recruited 440 subjects with hypercholesterolemia (mean age, 57 years; 43% men) from 21 primary health care centers-outpatient clinics into a prospective, multicentered intervention trial ...
Carlos, Lahoz +6 more
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To investigate some individual and genetic factors that may influence the response of low-density lipoprotein cholesterol (LDL-C) to pravastatin treatment, we recruited 440 subjects with hypercholesterolemia (mean age, 57 years; 43% men) from 21 primary health care centers-outpatient clinics into a prospective, multicentered intervention trial ...
Carlos, Lahoz +6 more
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Journal of Clinical Lipidology, 2011
There is little understanding of the reliability of laboratory measurements among clinicians. Low-density lipoprotein cholesterol (LDL-C) measurement is the cornerstone of cardiovascular risk assessment and prevention, but it is fraught with error. Therefore, we have reviewed issues related to accuracy and precision for the measurement of LDL-C and the
John H, Contois +2 more
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There is little understanding of the reliability of laboratory measurements among clinicians. Low-density lipoprotein cholesterol (LDL-C) measurement is the cornerstone of cardiovascular risk assessment and prevention, but it is fraught with error. Therefore, we have reviewed issues related to accuracy and precision for the measurement of LDL-C and the
John H, Contois +2 more
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Calculation of Low-Density Lipoprotein Cholesterol
Archives of Internal Medicine, 1991To the Editor.— In their article, Leighton et al1used Systeme International (SI) units to report their results with the corresponding traditional units in brackets. However, the equation they included in their "Methods" section for the calculation of low-density lipoprotein cholesterol (LDL-C) can be applied only with the latter units.2The correct ...
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Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007
A study to determine the utilization of calculated low density lipoprotein (c-LDL) cholesterol and measured low density lipoprotein (m-LDL) cholesterol was conducted. The test results of total cholesterol, triglyceride, HDL-cholesterol and m-LDL-cholesterol from the same individuals aged > or = 18 years who had the tests done at the Department of ...
Wanida, Wongtiraporn +6 more
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A study to determine the utilization of calculated low density lipoprotein (c-LDL) cholesterol and measured low density lipoprotein (m-LDL) cholesterol was conducted. The test results of total cholesterol, triglyceride, HDL-cholesterol and m-LDL-cholesterol from the same individuals aged > or = 18 years who had the tests done at the Department of ...
Wanida, Wongtiraporn +6 more
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The Journal of Applied Laboratory Medicine
Abstract Background Low-density lipoprotein cholesterol (LDL-C) is directly associated with coronary artery disease (CAD) risk. Subfractionation of LDL enables differentiation between large-buoyant LDL (>20.5 nm) and small-dense LDL (≤20.5 nm).
Nicholas E Larkey +4 more
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Abstract Background Low-density lipoprotein cholesterol (LDL-C) is directly associated with coronary artery disease (CAD) risk. Subfractionation of LDL enables differentiation between large-buoyant LDL (>20.5 nm) and small-dense LDL (≤20.5 nm).
Nicholas E Larkey +4 more
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