Results 111 to 120 of about 10,282,441 (287)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Low-dose lung CT: Optimizing diagnostic radiation dose – A phantom study

European Journal of Radiology Open
Background/purpose: To investigate a quantitative method for assessing image quality of low dose lung computed tomography (CT) and find the lowest exposure dose providing diagnostic images.
Michael Zellner, Sebastian Tschauner, Mathias S. Weyland, Peter Eggenberger Hotz, Stephan Scheidegger, Christian J. Kellenberger   +5 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Hydrogel‐Based 3D‐Printed Anthropomorphic Breast Phantom for Emulating Mechanical and Dielectric Properties of Mammary Tissue. Applications in Microwave Imaging

Advanced Functional Materials, EarlyView.
A 3D‐printable breast phantom is developed using patient‐derived MRI data and hydrogels that replicate the dielectric properties of healthy and cancerous tissues. Mechanical and dielectric characterization confirm its suitability for microwave imaging.
Carlos M. Andreu, Daniel Álvarez Sánchez‐Bayuela, Gianluigi Tiberi, Eliana Canicattì, Agostino Monorchio, Ester Vázquez   +5 more
wiley   +1 more source

Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals

Advanced Functional Materials, EarlyView.
The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner, Julian Fanelli, Vinh Xuan Truong, Rob Jones, Jens Gaitzsch, Christopher Barner‐Kowollik   +5 more
wiley   +1 more source

Low-Dose Radiation-Induced Effects on Cognitive Function

Hanggong uju uihakoeji
The relation between the low-dose radiation and the cognitive decline remains limited and controversial. However, the increasing use of high-dose radiation for medical purposes and some historical radiation-related accidents indicated that the low ...
Gyutae Kim, Kyu-Sung Kim
doaj   +1 more source

Pathway-based analyses of gene expression profiles at low doses of ionizing radiation

Frontiers in Bioinformatics
Radiation exposure poses a significant threat to human health. Emerging research indicates that even low-dose radiation once believed to be safe, may have harmful effects.
Xihaier Luo, Seyednami Niyakan, Patrick Johnstone, Sean McCorkle, Gilchan Park, Vanessa López-Marrero, Shinjae Yoo, Edward R. Dougherty, Xiaoning Qian, Xiaoning Qian, Francis J. Alexander, Shantenu Jha, Shantenu Jha, Byung-Jun Yoon, Byung-Jun Yoon   +14 more
doaj   +1 more source

From Bulk to Colloidal Nanocrystals: Top‐Down Synthesis of Highly Luminescent Cs2ZrCl6:Te4+ Double Perovskite Nanocrystals for X‐Ray Imaging

Advanced Functional Materials, EarlyView.
Top‐down ultrasonication produces highly emissive Cs2ZrCl6:Te4+ nanocrystals (NCs) with a PLQY of 65%, which is higher compared to that of the NCs synthesized by typical bottom‐up hot‐injection synthesis. The colloidal Cs2ZrCl6:Te4+ NCs have been found to be potential candidates for x‐ray scintillation imaging.
Yang Liu, Ye Wu, Hongpeng Liu, Cong Cui, Iago López‐Fernández, Nadesh Fiuza‐Maneiro, Sergio Gómez‐Graña, Yingjun Chai, Zhicheng Wang, Yusheng Wu, Laishi Li, Xiaoming Li, Lakshminarayana Polavarapu   +12 more
wiley   +1 more source

Involvement of GSTP1 in low dose radiation-induced apoptosis in GM12878 cells

Ecotoxicology and Environmental Safety
Background: Low-dose ionizing radiation-induced protection and damage are of great significance among radiation workers. We aimed to study the role of glutathione S-transferase Pi (GSTP1) in low-dose ionizing radiation damage and clarify the impact of ...
Jian Cui, Linwei Li, Shuang Wei, Yuanyun Wei, Yaqi Gong, Hongxia Yan, Yueqiu Yu, Xiang Lin, Hui Qin, Guoqing Li, Lan Yi   +10 more
doaj   +1 more source

Covalent Functionalization of 2D Semiconductors: A Roadmap to Advanced Electronic Devices

Advanced Functional Materials, EarlyView.
This Review presents recent advances in the covalent functionalization strategies for two‐dimensional semiconductors and their implementation in modern technologies. Layered materials are modified through diverse molecular chemistries (e.g., thiols, diazonium salts, alkyl halides, and electron‐deficient species) to tailor their surface properties ...
Ramiro Quirós‐Ovies, Bin Han, Paolo Samorì   +2 more
wiley   +1 more source