Results 31 to 40 of about 17,769,272 (338)

Design of a transrectal ultrasonic guided prostate low dose rate brachytherapy robot [PDF]

Mechanical Sciences, 2022
Transrectal prostate brachytherapy (BT) can effectively treat prostate cancer. During the operation, doctors need to hold the ultrasound probe for repeated adjustments, which makes it difficult to ensure the efficiency, accuracy, and safety of the ...
X. Dai, X. Dai, Y. Zhang, Y. Zhang, J. Jiang, J. Jiang, B. Li, B. Li, S. Zuo, S. Zuo   +9 more
doaj   +1 more source

Oxidative Stress Levels and DNA Repair Kinetics in Senescent Primary Human Fibroblasts Exposed to Chronic Low Dose Rate of Ionizing Radiation

Frontiers in Bioscience-Landmark, 2023
Background: Exposure to low dose rate (LDR) radiation may accelerate aging processes. Previously, we identified numerous LDR-induced pathways involved in oxidative stress (OS) and antioxidant systems, suggesting that these pathways protect against ...
Traimate Sangsuwan, Ali Pour Khavari, Evelina Blomberg, Tajanena Romell, Paulo Roberto D'auria Vieira De Godoy, Mats Harms-Ringdahl, Siamak Haghdoost   +6 more
doaj   +1 more source

Formation of γH2AX and pATM Foci in Human Mesenchymal Stem Cells Exposed to Low Dose-Rate Gamma-Radiation

International Journal of Molecular Sciences, 2019
DNA double-strand breaks (DSB) are among the most harmful DNA lesions induced by ionizing radiation (IR). Although the induction and repair of radiation-induced DSB is well studied for acute irradiation, responses to DSB produced by chronic IR exposures ...
S. Ulyanenko, M. Pustovalova, S. Koryakin, E. Beketov, A. Lychagin, L. Ulyanenko, A. Kaprin, A. Grekhova, Alexandra M. Ozerova, I. Ozerov, N. Vorobyeva, P. Shegay, S. Ivanov, S. Leonov, D. Klokov, A. Osipov   +15 more
semanticscholar   +1 more source

Scientific Risk Estimation on Health Effects of Low Dose and Low Dose-Rate Radiation - An Overview

Data Science Journal, 2009
Estimation of the scientific risks of high dose radiation has been successfully quantified by many studies using several different approaches. However, the risk for low and low dose-rate radiation is obscure because of a lack of evidence.
Tetsuya Ono, Dmytro Grodzinsky
doaj   +1 more source

Cancer mortality after low dose exposure to ionising radiation in workers in France, the United Kingdom, and the United States (INWORKS): cohort study

British medical journal, 2023
Objective To evaluate the effect of protracted low dose, low dose rate exposure to ionising radiation on the risk of cancer. Design Multinational cohort study. Setting Cohorts of workers in the nuclear industry in France, the UK, and the US included in a
David B Richardson, K. Leuraud, D. Laurier, M. Gillies, R. Haylock, K. Kelly-Reif, S. Bertke, R. Daniels, I. Thierry-Chef, M. Moissonnier, A. Kesminiene, M. Schubauer-Berigan   +11 more
semanticscholar   +1 more source

Validation of American association of physicists in medicine tg 43 dosimetry data in commercial treatment planning system

Journal of Medical Physics, 2021
Aims This study aimed to validate the dosimetric data of low-energy photon-emitting low-dose rate (LE-LDR) brachytherapy seed sources in commercial treatment planning system (TPS).
Sathiyan Saminathan, K Maheshraja, K M Ganesh   +2 more
doaj   +1 more source

Perturbed transcriptional profiles after chronic low dose rate radiation in mice.

PLoS ONE, 2021
Adverse health outcomes of ionizing radiation given chronically at low dose rates are highly debated, a controversy also relevant for other stressors.
Hildegunn Dahl, Dag M Eide, Torstein Tengs, Nur Duale, Jorke H Kamstra, Deborah H Oughton, Ann-Karin Olsen   +6 more
doaj   +1 more source

Radioactive Iodine-125 in Tumor Therapy: Advances and Future Directions

Frontiers in Oncology, 2021
Radioactive iodine-125 (I-125) is the most widely used radioactive sealed source for interstitial permanent brachytherapy (BT). BT has the exceptional ability to deliver extremely high doses that external beam radiotherapy (EBRT) could never achieve ...
Shuhua Wei, Chunxiao Li, Mengyuan Li, Yan Xiong, Yuliang Jiang, Haitao Sun, Bin Qiu, Christopher J. Lin, Junjie Wang   +8 more
doaj   +1 more source

Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation

Epigenetics, 2023
Ionizing radiation (IR) impact cellular and molecular processes that require chromatin remodelling relevant for cellular integrity. However, the cellular implications of ionizing radiation (IR) delivered per time unit (dose rate) are still debated.
Hildegunn Dahl, Jarle Ballangby, Torstein Tengs, Marcin W. Wojewodzic, Dag M. Eide, Dag Anders Brede, Anne Graupner, Nur Duale, Ann-Karin Olsen   +8 more
doaj   +1 more source

Gamma Low-Dose-Rate Ionizing Radiation Stimulates Adaptive Functional and Molecular Response in Human Aortic Endothelial Cells in a Threshold-, Dose-, and Dose Rate–Dependent Manner

Dose-Response, 2018
A central question in radiation protection research is whether low-dose and low-dose-rate (LDR) exposures to ionizing radiation play a role in progression of cardiovascular disease.
Juliana Vieira Dias, C. Gloaguen, D. Kereselidze, L. Manens, K. Tack, T. Ebrahimian   +5 more
semanticscholar   +1 more source