Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia
European journal of internal medicine, 2020 Highlights • Pneumonia with respiratory failure represents the main cause of death in COVID-19.• Hyperinflammation plays an important role in COVID-19 lung damage.• Tocilizumab might be helpful to treat COVID-19 related pneumonia.• 8% vs 57% of deaths ...
R. Capra +6 more
semanticscholar +1 more source
Brachytherapy, 2017 Purpose Rates of rectal toxicity after low-dose-rate brachytherapy for prostate cancer are dependent on rectal dose which is associated with rectal distance from prostate and implanted seeds. Placement of a hydrogel spacer between the prostate and rectum
A. Taggar +8 more
semanticscholar +1 more source
Low dose ionising radiation produces too few ROS to directly affect antioxidant concentrations in cells [PDF]
, 2012 It has been hypothesized that radiation-induced oxidative stress is the mechanism for a wide range of negative impacts on biota living in radioactively contaminated areas around Chernobyl.
Smith, Jim +5 more
core +1 more source
ENHANCED LOW DOSE RATE SENSITIVITY (ELDRS) AND REDUCED LOW DOSE RATE SENSITIVITY (RLDRS) IN BIPOLAR DEVICES [PDF]
, 2020 Possible physical mechanism of enhanced low dose rate sensitivity (ELDRS) and reduced low dose rate sensitivity (RLDRS)in bipolar devices is described. Modification of the low dose rate conversion model is presented.
Felitsyn, Vladislav +6 more
core +1 more source
Use of Pulsed Low–Dose Rate Radiotherapy in Refractory Malignancies
Translational Oncology, 2018 BACKGROUND: Most tumor cell lines exhibited low-dose hyperradiosensitivity (LDHRS) to radiation doses lower than 0.3 Gy. Pulsed low–dose rate radiotherapy (PLDR) took advantage of LDHRS and maximized the tumor control process.
Jing Yan +11 more
doaj +1 more source
The variance-covariance method: Microdosimetry in time-varying low dose-rate radiation fields [PDF]
, 1988 The variance-covariance method is employed at low doses and in radiation fields of low dose rates from an241Am (4 nGy/s) and a90Sr (300 nGy/s) source. The preliminary applications and results illustrate some of the potential of the method, and show that ...
Breckow, Joachim +7 more
core +1 more source
Immunomodulatory properties and molecular effects in inflammatory diseases of low-dose X-irradiation [PDF]
, 2012 Inflammatory diseases are the result of complex and pathologically unbalanced multicellular interactions. For decades, low-dose X-irradiation therapy (LD-RT) has been clinically documented to exert an anti-inflammatory effect on benign diseases and ...
Seegenschmiedt, Michael H. +26 more
core +1 more source
Establishment of low-dose rate X-ray radiation quality and calibration of the instruments
He jishu, 2022 BackgroundCalibration is an important way to assess the performance of radiation monitoring instruments and to ensure their accuracy and reliability for measurement.PurposeThis study aims to solve the traceability problem of dose meters at low dose rate ...
LI Mengyu +7 more
doaj +1 more source
Low-dose or low-dose-rate ionizing radiation–induced bioeffects in animal models
Journal of Radiation Research, 2016 Animal experimental studies indicate that acute or chronic low-dose ionizing radiation (LDIR) (≤100 mSv) or low-dose-rate ionizing radiation (LDRIR) (
Feng-Ru Tang, W. Loke, B. Khoo
semanticscholar +1 more source
Journal of Clinical Oncology, 2021 PURPOSE Nivolumab received US Food and Drug Administration approval as a single agent or in combination with ipilimumab in patients with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) that ...
H. Lenz +16 more
semanticscholar +1 more source