Results 61 to 70 of about 1,044,650 (277)

Recreational Female CrossFit Athletes and Low Energy Availability

, 2021
CrossFit is a demanding sport in which athletes perform constantly varied, functional movements at a high intensity, therefore requiring an adequate energy availability to avoid negative health and performance consequences.
Kuch, Alison
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Transportation Energy Futures Series: Alternative Fuel Infrastructure Expansion: Costs, Resources, Production Capacity, and Retail Availability for Low-Carbon Scenarios

, 2013
Achieving the Department of Energy target of an 80% reduction in greenhouse gas emissions by 2050 depends on transportation-related strategies combining technology innovation, market adoption, and changes in consumer behavior.
Heath, G., Webster, K. W., Sandor, D., Melaina, M. W., Vimmerstedt, L., Warner, E., Steward, D.   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

System modelling and optimization of a low temperature local hybrid energy system based on solar energy for a residential district

, 2022
Utilizing solar energy for heat supply can reduce CO2 emissions and mitigate global climate change. In the Nordic region (e.g., Iceland and Finland), a tremendous seasonal mismatch exists between the availability of solar radiation and building heating ...
Hirvonen, Janne, Virtanen, Markku, Liang, Yumin, Yuan, Xiaolei, Kosonen, Risto, Pan, Yiqun, Heikari, Lassi   +6 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Survey of Multi-Source Energy Harvesting Systems

, 2013
Energy harvesting allows low-power embedded devices to be powered from naturally-occurring or unwanted environmental energy (e.g. light, vibration, or temperature difference).
Geoff V. Merrett, Benini, Luca, Bashir M. Al Hashimi, Weddell, Alexander S., Alex S. Weddell, Al-Hashimi, Bashir, Merrett, Geoff V., Davide Brunelli, Michele Magno, Bashir M. Al-Hashimi, Luca Benini, Brunelli, Davide, Magno, Michele   +12 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Sensitivity Studies of a Low Temperature Low Approach Direct Cooling Tower for Building Radiant Cooling Systems

, 2012
Recent interest in cooling towers as a mechanism for producing chilled water, together with the evolution of radiant cooling, have prompted a review of evaporative cooling in temperate maritime climates.
Nasrabadi, Mehdi, Costelloe, Ben, Finn, Donal, Nasrabadi, Medhi   +3 more
core   +1 more source