Results 71 to 80 of about 11,585,015 (293)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ADVERSE EFFECTS OF LOW FREQUENCY NOISE ON ALVEOLAR BONE OF MICE, AN UNSEEN DILEMMA

open access: yesPakistan Armed Forces Medical Journal, 2018
Objective: To observe the destructive effects of low frequency noise on periodontium with special emphasis on the alveolar bone. Study Design: Laboratory based randomized control study.
Toqeer Ahmed Iqbal   +2 more
doaj   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Low frequency noise in advanced Si bulk and SOI MOSFETs

open access: yesJournal of Telecommunications and Information Technology, 2005
A review of recent results concerning the low frequency noise in modern CMOS devices is given. The approaches such as the carrier number and the Hooge mobility fluctuations used for the analysis of the noise sources are presented and illustrated through
Jalal Jomaah   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Does low frequency noise affect human mental performance?

open access: yesArchives of Acoustics, 2004
To study the influence of low frequency noise (LFN) on mental performance and subjective well-being, 192 male subjects, categorised in terms of sensitivity to noise in general, and to LFN in particular, worked with four standardised ...
M. Pawlaczyk-Łuszczyńska   +5 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Low phase noise microwave frequency synthesizer for cold atom clock

open access: yesAIP Advances, 2019
We present a low phase noise microwave frequency synthesizer for the integrating sphere cold atom clock. The synthesizer is based on an ultralow-phase-noise oven-controlled crystal oscillator and employs a phase-locking technique.
Mingyuan Yu   +8 more
doaj   +1 more source

Low frequency damping of metal panels in ambient Air [PDF]

open access: yes, 2008
Mathematical models of structural dynamics are widely used and applied in many branches of science and engineering and it has been argued that many of the shortfalls with these models are due to the fact that the physics of joint dynamics are not ...
Paul Cunningham (1251771)   +8 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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