Results 61 to 70 of about 1,501,574 (297)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Low frequency noise in chemical vapor deposited MoS2

, 2013
Inherent low frequency noise is a ubiquitous phenomenon, which limits operation and performance of electronic devices and circuits. This limiting factor is very important for nanoscale electronic devices, such as 2D semiconductor devices.
Laskar, Masihhur R., Lu, Wu, Luo, Xinhang, Ma, Lu, Rajan, Siddharth, Wang, Yuji, Wu, Yiying, Zhang, Ningjiao   +7 more
core   +1 more source

Amplitude noise reduction in semiconductor lasers with weak, dispersive optical feedback [PDF]

, 1994
We present the theory and measurements of the amplitude noise spectrum from a semiconductor laser with weak optical feedback (Pfb/Pout ~10^-6) from an external cavity containing an element of dispersive loss.
Boyd, R., Kitching, J., Shevy, Y., Yariv, A.   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Model Implementation of Lorentzian Spectra for Circuit Noise Simulations in the Frequency Domain

IEEE Journal of the Electron Devices Society, 2022
This work presents a new method for the Verilog-A implementation of Lorentzian noise models, in a module called VERILOR, which can automatically generate either Lorentzian or 1/f-like noise spectra depending on the trap density and gate oxide area, for ...
Angeliki Tataridou, Gerard Ghibaudo, Christoforos Theodorou   +2 more
doaj   +1 more source

Noise properties of a resonance-type spin-torque microwave detector

, 2011
We analyze performance of a resonance-type spin-torque microwave detector (STMD) in the presence of noise and reveal two distinct regimes of STMD operation.
Andrei Slavin, Elena Bankowski, Gennadiy Melkov, Lukyanchikova N. B., Oleksandr Prokopenko, Pozar D. M., Thomas Meitzler, Vasil Tiberkevich   +7 more
core   +1 more source

Shapiro Effect as a Possible Cause of the Low-Frequency Pulsar Timing Noise in Globular Clusters [PDF]

, 2005
A prolonged timing of millisecond pulsars has revealed low-frequency uncorrelated noise, presumably of astrophysical origin, in the pulse arrival time (PAT) residuals for some of them.
A. E. Rodin, A. G. Lyne, A. V. Zakharov, A.G. Lyne, B. Bertotti, B. Guinot, D. F. Elliott, D. N. Matsakis, E. B. Fomalont, E. J. Groth, F. Camilo, F. D’Alessandro, G. Petit, I. I. Shapiro, I. R. King, J. H. Taylor, J. H. Taylor, J. H. Taylor, J. M. Cordes, J. M. Cordes, K. J. Joshi, L. A. Rawley, L. Spitzer Jr., M. Bailes, M. M. Davis, M. Soffel, M. V. Sazhin, M. V. Sazhin, O. V. Doroshenko, O. V. Doroshenko, R. Blandford, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, S. M. Kopeikin, T. I. Larchenkova, T. I. Larchenkova, T. V. Smirnova, V. A. Brumberg, V. A. Brumberg, V. M. Kaspi, W. E. Harris, Y. Bard, Yu. P. Ilyasov   +50 more
core   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source