Results 141 to 150 of about 3,506,686 (362)

Long-Term Cognitive Functioning and Psychological Well-Being in Surgically Treated Patients with Low-Grade Glioma

open access: green, 2017
Fabio Campanella   +7 more
openalex   +2 more sources

Mutual Contrastive Low-rank Learning to Disentangle Whole Slide Image Representations for Glioma Grading [PDF]

open access: green, 2022
Lipei Zhang   +5 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Controller Hardware-in-the-Loop Simulation of SOFC-GT Hybrid System

open access: yesEnergies
The solid oxide fuel cell–gas turbine (SOFC-GT) hybrid system is confronted with challenges related to system integration and coordinated control. In this study, a Controller Hardware-in-the-Loop Simulation (C-HILS) platform is constructed to validate ...
Yuandong Liu   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Instability Analysis of Two-Phase Flow in Parallel Rectangular Channels for Compact Nuclear Reactors

open access: yesEnergies
In this paper, a numerical study of two-phase flow instability in parallel rectangular channels is presented. Using the homogeneous flow model, marginal stability boundaries (MSBs) are derived in the parameter space defined by the phase change number ...
Simiao Tang   +10 more
doaj   +1 more source

Management of Diffuse Low-Grade Glioma: The Renaissance of Robust Evidence [PDF]

open access: gold, 2020
Karanbir Brar   +7 more
openalex   +1 more source

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