Results 201 to 210 of about 1,399,259 (268)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Very low-grade albuminuria is linked to arterial stiffness in a population-based cohort. [PDF]

Am J Prev Cardiol
Walendy V, Gekle M, Grossmann C, Kluttig A, Kraus FB, Ludwig-Kraus B, Mikolajczyk R, Schmid T, Thews O, Wienke A, Zinkhan M, Girndt M.   +11 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Recurrent Intra-abdominal Low-Grade Fibromyxoid Sarcoma Managed With Multivisceral Resections: A Case Report. [PDF]

Cureus
Kirov K, Varbanov P, Mirinchev N.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Direct optimization of the probability of lesion origin in proton treatment planning for low-grade glioma patients. [PDF]

Med Phys
Ortkamp T, Sallem H, Harrabi S, Frank M, Jäkel O, Bauer J, Wahl N.   +6 more
europepmc   +1 more source

PSMC4 promotes low-grade glioma progression and predicts poor prognosis. [PDF]

Eur J Med Res
Ming W, Yunhui S, Dongjuan C, Yanhong Z, Huijie B, Hui Z, Liquan Q, Zhongliang D, Liping W.   +8 more
europepmc   +1 more source

Low-Grade Appendiceal Mucinous Neoplasm With Discontinuous Mucin Infiltration Into the Cecal Wall: A Case Report. [PDF]

Cureus
Tabara N, Otani Y, Seiya Y, Nakamura T.
europepmc   +1 more source

Clinical Features Associated With Malignant Transformation of Low-Grade Dysplasia. [PDF]

J Oral Pathol Med
Laronde DM, Berkowitz M, Kerr AR, Hade EM, Siriruchatanon M, Rosin MP, Kang SK.   +6 more
europepmc   +1 more source

Beyond the Inflamed Appendix: Low-Grade Appendiceal Mucinous Neoplasm-Emphasis on Macroscopic Findings. [PDF]

Diagnostics (Basel)
Csonka B, Ferenczi Á, Sejben A.
europepmc   +1 more source