Low impact development technologies for mitigating climate change: Summary and prospects
National Science OpenMany cities are adopting low impact development (LID) technologies (a type of nature-based solution) to sustainably manage urban stormwater in future climates.
Zhang Zhonghao, Valeo Caterina
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LID-BMPs planning for urban runoff control and case study
Shui kexue jinzhan, 2014 Low Impact Development type's Best Management Practices (LID-BMPs) have been regarded as cost-effective measures for mitigating urban runoff impacts. However,as the implementations of LID-BMPs are interacted with many factors,the research on LID-BMPs ...
JIA Haifeng +3 more
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Estimating Regionalized Planning Costs of Green Infrastructure and Low-Impact Development Stormwater Management Practices: Updates to the US Environmental Protection Agency's National Stormwater Calculator. [PDF]
J Sustain Water Built Environ, 2021 Bernagros JT +3 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Impact Strategy Development: Questions Bank and Interview Guide
The tool ‘Impact Strategy Development: Questions Bank and Interview Guide’ consists of (1) a three step interview guide and (2) an Excel file with a questions bank to use and tailor for your interviews or other methods for engaging with your community ...
Evaluating Societal Impact
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Development Effectiveness Overview (DEO) 2018
, 2018 The Development Effectiveness Overview (DEO) is an annual report produced by the IDBG to show the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
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IDB Group Selected Development Contributions 2016-2019
, 2020 This infographic shows selected IDB Group\u27s contributions to the Sustainable Development Goals (SDGs) reported through the Group\u27s Corporate Results Framework between 2016 and ...
Inter-American Development Bank
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source