Results 121 to 130 of about 29,815,926 (313)

Low Impact Development for Stormwater Quantity and Quality [PDF]

open access: yesJournal of Water Management Modeling, 2010
Low impact development, also known as LID, is an innovative stormwater management approach modeled after nature. This chap-ter provides information and case st…
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Financing the Future with the IDB Group [PDF]

open access: yes, 2019
Mobilizing resources is critical to the implementation of the 2030 Agenda and multilateral development banks in particular have been called upon to crowd-in additional financing for the Sustainable Development Goals (SDGs).
Inter-American Development Bank
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Low impact development technologies for mitigating climate change: Summary and prospects

open access: yesNational Science Open
Many cities are adopting low impact development (LID) technologies (a type of nature-based solution) to sustainably manage urban stormwater in future climates.
Zhang Zhonghao, Valeo Caterina
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Optimization of Low-Impact Development Scheme for Communities

open access: yesRenmin Zhujiang, 2023
The benefits of different low-impact development (LID) combinations are compared and quantified from the perspective of sponge cities to alleviate the problem of urban waterlogging.For a residential project in Beijing,the stormwater management model (SWMM) and the analytic hierarchy process (AHP) are used to analyze three different schemes with ...
HU Jinhui, PANG Aoxuan, SUN Yingna
openaire   +1 more source

Impact Framework 2024-2030: Executive Summary

open access: yes
The Impact Framework is the highest-level tool of the IDB, IDB Invest, and IDB Lab for monitoring performance and achieving strategic objectives under IDBStrategy.
Inter-American Development Bank
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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