Results 131 to 140 of about 29,815,926 (313)

The Impact of Low-Altitude Economy on the Development of Tourism

open access: yesFrontiers in Business, Economics and Management
This paper focuses on the development of China's low-altitude economy and its impact on the tourism industry. Through literature analysis, it defines low-altitude economy and low-altitude tourism, and conducts in-depth research on the industrial chain and development directions of the low-altitude economy. By examining application scenarios and typical
Juntong Chen, Dong Li, Yuhang Ren
openaire   +1 more source

Development Effectiveness Overview 2015: Summary

open access: yes, 2016
The summary of the Development Effectiveness Overview (DEO) presents the main takeaways of the DEO, which is the Inter-American Development Bank\u27s annual report about the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Climate Change and Sustainability: A Newsletter of the Inter-American Development Bank: Vol. 1: November-December 2011

open access: yes, 2011
The IDB\u27s mandate to promote development in the Latin America and Caribbean region includes a strategic approach along a climate-resilient and low-carbon path.
Inter-American Development Bank
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Development Effectiveness Overview (DEO) 2015

open access: yes, 2016
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB to show the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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