Results 131 to 140 of about 31,660,953 (313)
Development Effectiveness Overview (DEO) 2019: Executive Summary
, 2019 The Development Effectiveness Overview (DEO) is the annual flagship report of the IDB Group, which showcases the Group\u27s contribution towards the development of its 26 borrowing member countries in Latin America and the Caribbean. The 2019 DEO summary
Inter-American Development Bank
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Impact Strategy Development: Workshops to Co-create your Strategy
This tool serves as a guide for conducting workshops that enable strategic planning within your school. These workshops provide a structured environment for refection and dialogue, which empowers participants to articulate their aspirations for societal ...
Evaluating Societal Impact
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Development Effectiveness Overview (DEO) 2018: Executive Summary
, 2018 The summary of the Development Effectiveness Overview (DEO) presents the main takeaways of the DEO, which is the Inter-American Development Bank\u27s annual report about the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Testing of the Storm Water Management Model Low Impact Development Modules. [PDF]
J Am Water Resour Assoc, 2020 Platz M, Simon M, Tryby M.
europepmc +1 more source
, 2011 Information and communication technologies (ICT)--cell phones, computers, Internet--hold great promise but greater access alone cannot bring about economic development. This is a major finding of the IDB\u27s latest edition of its flagship Development in
Inter-American Development Bank
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source