Results 111 to 120 of about 29,815,926 (313)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Progress Report (2014-2015) of the MDB Working Group on Sustainable Transport [PDF]

open access: yes, 2015
1. In the third year of the Multilateral Development Banks¿1 (MDBs) Joint Statement of 2012, our eight MDBs are on target to meet the goal of the Commitment to Sustainable Transport (hereafter the Rio+20 Commitment) to provide more than $175 billion of ...
Inter-American Development Bank
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Urban flood disaster risk management using multi-criteria decision-making methods: A scoping review

open access: yesInternational Journal of Strategic Property Management
Statistical data indicates a rising trend in the frequency and unpredictability of floods globally. Regions traditionally less affected by flooding are reportedly experiencing an increased impact, underscoring the widespread nature of this phenomenon ...
Gintarė Piaseckienė   +1 more
doaj   +1 more source

Modeling Low Impact Development Alternatives with SWMM [PDF]

open access: yesJournal of Water Management Modeling, 2010
The U.S. Environmental Protection Agency’s Office of Water is actively promoting the use of Low Impact Development (LID) practices to help protect and restore …
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Unveiling Participation Dynamics: A Comparative Study of Green Infrastructure Practices

open access: yesLand
Outcomes for urban green infrastructure (GI) and low-impact development (LID) vary; thus, we ask when and how public participation affects performance. We apply a four-dimensional framework—breadth (who participates), depth (decision influence), identity
Mingwei Yuan, Jin-Oh Kim
doaj   +1 more source

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