Results 81 to 90 of about 14,237,293 (248)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A Design Methodology for Low-Loss Interconnects Featuring Air Cavities and Periodically Nonuniform Widths

Applied Sciences
Power consumption in interconnects is a critical constraint on performance improvements in integrated circuits. This paper proposes a novel design methodology to minimize loss in interconnects and address this limitation.
Yan Shao, Mingjie Zhang
doaj   +1 more source

Low-loss single-mode hybrid-lattice hollow-core photonic crystal fiber

, 2020
The remarkable recent demonstrations in ultralow loss Inhibited-Coupling (IC) hollow-core photonic crystal fibers (HCPCFs) place them as serious candidates for the next-generation of long-haul fiber optics systems.
Benoît Debord (4455658), Fabio Giovanardi (14388750), Luca Vincetti (14388753), Fetah Benabid (4455649), Frédéric Gérôme (4544728), Jonas H. Osório (14359026), Frédéric Delahaye (14364300), Foued Amrani (10004036)   +7 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Progress in Mechanized Harvesting Technologies and Equipment for Minor Cereals: A Review

Agriculture
Minor cereals are an important part of the Chinese grain industry, accounting for about 8 percent of the country’s total grain-growing area. Minor cereals include millet, buckwheat, Panicum miliaceum, and other similar grains. Influenced by topographical
Xiaojing Ren, Fei Dai, Wuyun Zhao, Ruijie Shi, Junzhi Chen, Leilei Chang   +5 more
doaj   +1 more source

Design of Low-Loss Surface-Plasmon Quantum Cascade Lasers

, 2009
A low-loss waveguide design for the mid-infrared surface-plasmon quantum cascade lasers (QCLs) is proposed. A waveguide loss of 6.5-8 cm(-1) with a confinement factor above 50% is obtained by modulating the doping concentration and thickness of the In0 ...
Zhang W, Yin W, Zhang QD, Lu, QY, Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, POB 912, Beijing 100083, Peoples R China. E-mail Address: fqliu@red.semi.ac.cn, Gao Y, Wang LJ, Liu WF, Lu QY, Wang ZG, Liu FQ, Wei Zhang, Quan-De Zhang, Quan-Yong Lu, Wen Yin, Li-Jun Wang, Wan-Feng Liu, Yu Gao, Feng-Qi Liu, Zhan-Guo Wang   +18 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An Ultra-Broadband Conductor-Backed Coplanar Waveguide with Sine Edges

Sensors
In this paper, a conductor-backed coplanar waveguide with sine edges (CBCPW-SE), consisting of a conductor-backed coplanar with periodic sine edges supported by a dielectric substrate, is proposed as a promising new transmission line (TL) at millimeter ...
Tingting Xie, Pengwei Gong, Xiaohe Cheng, Tao Xiu, Yuan Yao   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Research on a New Structure of High-Birefringence, Low-Loss Hollow-Core Photonic Bandgap Fibre

Photonics
Hollow-core microstructured optical fibres exhibit excellent properties, such as a low loss, tuneable high birefringence, and low nonlinearity, finding extensive applications across communications, industry, agriculture, medicine, military, and sensing ...
Fang Tan, Shunfa Cui, Zhitao Zhang, Songsong Ge, Dexiao Chen, Yanke Zhang, Dechun Zhou   +6 more
doaj   +1 more source