Results 101 to 110 of about 6,573,875 (320)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

SEARCH FOR LOW MASS HIGGS AT THE TEVATRON [PDF]

High Energy Physics, 2007
ICHEP Moscow 2006 ...
openaire   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Nutrition interventions to treat low muscle mass in cancer

Journal of Cachexia, Sarcopenia and Muscle, 2020
Many patients with cancer experience poor nutritional status, which detrimentally impacts clinical outcomes. Poor nutritional status in cancer is primarily manifested by severe muscle mass (MM) depletion, which may occur at any stage (from curative to ...
Carla M. Prado, Sarah A. Purcell, Alessandro Laviano   +2 more
doaj   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Low mass dimuons within a hybrid approach

, 2011
We analyse dilepton emission from hot and dense hadronic matter using a hybrid approach based on the Ultrarelativistic Quantum Molecular Dynamics (UrQMD) transport model with an intermediate hydrodynamic stage for the description of heavy-ion collisions ...
Elvira Santini, Gale C, Graf G, Marcus Bleicher, Mazzoni M A (HELIOS/3), Petersen H, Rapp R, Santini E   +7 more
core   +1 more source

Formation of a metastable nanostructured mullite during Plasma Electrolytic Oxidation of aluminium in “soft” regime condition

Materials & Design, 2019
This paper demonstrates the possibility of producing a lamellar ceramic nanocomposite at the top-most surface of oxide coatings grown with the Plasma Electrolytic Oxidation process (PEO).
J. Martin, A. Nominé, V. Ntomprougkidis, S. Migot, S. Bruyère, F. Soldera, T. Belmonte, G. Henrion   +7 more
doaj  

Reliability of low mass toenail samples as biomarkers of chronic metal exposure. [PDF]

J Expo Sci Environ Epidemiol, 2023
Lin JJY, Koffman LJ, Tehrani MW, Chen R, Han SG, Sandler DP, Lawrence KG, Jackson WB, Dickerson AS, Ramachandran G, Engel LS, Rule AM.   +11 more
europepmc   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source