Results 161 to 170 of about 348,919 (331)

Reduced Oligodendrocyte Density and Axonal Caliber Associated With Mitochondrial Alterations in the White Matter of Chronically‐Starved Mice

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang, Annelie Zimmermann, Kaja Dickert, Hanna Rupprecht, Julia Priebe, Fabienne Haberland, Hanna‐Sophia Henschke, Katharina Schuster, Marcus Frank, Linda Frintrop   +9 more
wiley   +1 more source

Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home. The Tasman Study Group.

New England Journal of Medicine, 1996
M. Koopman, P. Prandoni, F. Piovella, P. Ockelford, D. Brandjes, J. van der Meer, A. Gallus, G. Simonneau, Colin H. Chesterman, M. Prins, P. Bossuyt, H. D. de Haes, A. van den Belt, L. Sagnard, Pascal d'Azemar, H. Büller   +15 more
semanticscholar   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

Exploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao, Yao Chen, Haimeng Yuan, Shuqian Yang, Hongyuan Zhang, Yuequan Wang, Shenwu Zhang, Qin Chen, Jin Sun, Zhonggui He, Cong Luo   +10 more
wiley   +1 more source

Unfractionated heparin versus low-molecular-weight heparin for venous thromboembolism prophylaxis in trauma

Journal of Trauma and Acute Care Surgery, 2017
Benjamin N. Jacobs, Anne H. Cain-Nielsen, Jill L. Jakubus, J. Mikhail, J. Fath, S. Regenbogen, M. Hemmila   +6 more
semanticscholar   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

Low-Molecular-Weight Heparin for Adult ICU Patients Who Require Thromboprophylaxis: Protocol for the INCEPT-Thromboprophylaxis Platform Trial Domain. [PDF]

Acta Anaesthesiol Scand
Eck R, Granholm A, Tøgern A, Jensen AKG, Jonmarker S, Sjövall F, Meijer K, Cronhjort M, Møller MH, Perner A, Keus F.   +10 more
europepmc   +1 more source

Outcomes and risk factors of hemorrhage in patients with resected brain metastases

International Journal of Cancer, EarlyView.
What's New? Brain metastases may present with hemorrhage, yet risk factors and clinical outcomes remain unclear. Based on a cohort of 880 patients with resected brain metastases, this study identified tumor volume and primary tumor histology (melanoma and non‐small cell lung cancer) as key predictors of hemorrhage.
Melisa S. Guelen, Kiarash Ferdowssian, Niklas Jung, Hava N. Celik, Andrea Dell'Orco, Semil Eminovic, Anton Früh, Majd Samman, Güliz Acker, Arend Koch, Helena Radbruch, Michael Scheel, Mike P. Wattjes, Julia Onken, Peter Vajkoczy, Nils Hecht, Jawed Nawabi, David Wasilewski   +17 more
wiley   +1 more source

Andexanet alfa for the reversal of the low-molecular-weight heparin enoxaparin. [PDF]

Res Pract Thromb Haemost
van Haaps TF, Benz AP, Xu L, Middeldorp S, Eikelboom JW, Milling TJ, Crowther M, Holer L, Nolan S, Ladenvall P, Lu G, Coppens M.   +11 more
europepmc   +1 more source

A comparison of low-molecular-weight heparin with unfractionated heparin for acute pulmonary embolism. The THESEE Study Group. Tinzaparine ou Heparine Standard: Evaluations dans l'Embolie Pulmonaire.

New England Journal of Medicine, 1997
G. Simonneau, H. Sors, B. Charbonnier, Y. Page, J. Laaban, R. Azarian, M. Laurent, J. Hirsch, E. Ferrari, J. Bosson, D. Mottier, B. Beau   +11 more
semanticscholar   +1 more source