Results 21 to 30 of about 21,048 (245)
Urinary retinol binding protein is a marker of the extent of interstitial kidney fibrosis. [PDF]
PLoS ONE, 2014 Currently, a non-invasive method to estimate the degree of interstitial fibrosis (IF) in chronic kidney disease is not available in routine. The aim of our study was to evaluate the diagnostic performance of the measurement of urinary low molecular ...
Nicolas Pallet +11 more
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A novel CLCN5 frame shift mutation responsible for Dent disease 1: Case report
Frontiers in Pediatrics, 2022 BackgroundDent disease is a group of inherited X-linked recessive renal tubular disorders. This group of disorders is characterized by low molecular weight proteinuria (LMWP), nephrocalcinosis, hypercalciuria and renal failure.Case presentationHere we ...
Jiajia Ni +6 more
doaj +1 more source
Indian Journal of Endocrinology and Metabolism, 2021 Purpose of the Study: Reversible proximal tubular dysfunction associated with distal renal tubular acidosis (dRTA) mimics type 3 RTA, a condition classically associated with features of both proximal RTA (pRTA) and dRTA.
Partha Pratim Chakraborty +5 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2019 Antisense oligonucleotide therapy has been reported to be associated with renal injury. Here, the mechanism of reversible proteinuria was investigated by combining clinical, pre-clinical, and in vitro data.
Manoe J. Janssen +10 more
doaj +1 more source
Next-Generation Sequencing in Early Diagnosis of Dent Disease 1: Two Case Reports
Frontiers in Medicine, 2018 Dent disease 1 is a rare X-linked recessive inherited disease, caused by pathogenic variants in the chloride voltage-gated channel 5 (CLCN5) gene. Dent disease 1 is characterized by low molecular weight (LMW) proteinuria, hypercalciuria, nephrocalcinosis,
Min Wen +10 more
doaj +1 more source
Stem Cell Research, 2021 Dent disease (DD) is a rare X-linked proximal tubulopathy associated with low molecular weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and phosphoruria, which may progress to chronic kidney disease (CKD).
Lidan Hu +7 more
doaj +1 more source
Brazilian Journal of Nephrology, 2012 Dent's disease type 1 is an X-linked tubular disease caused by mutations in the renal chloride channel CLCN-5, and it is characterized by low molecular weight proteinuria, hypercalciuria, nephrocalcinosis, and renal failure.
Maria Helena Vaisbich +5 more
doaj +1 more source
An overview of Dent disease [PDF]
Childhood Kidney Diseases, 2023 Dent disease is a rare inherited kidney tubulopathy caused by mutations in either the CLCN5 (Dent disease 1) or OCRL1 (Dent disease 2) genes, and which is often underdiagnosed in practice.
Eun Mi Yang, Seong Hwan Chang
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Generation of a human induced pluripotent stem cell line from a patient with dent disease
Stem Cell Research, 2023 Dent disease, an X-linked tubular disorder, is a rare condition that leads to low-molecular-weight proteinuria, hypercalciuria, kidney stones, and chronic kidney disease.
Xianying Fang +12 more
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Renal Effects and Underlying Molecular Mechanisms of Long-Term Salt Content Diets in Spontaneously Hypertensive Rats. [PDF]
PLoS ONE, 2015 Several evidences have shown that salt excess is an important determinant of cardiovascular and renal derangement in hypertension. The present study aimed to investigate the renal effects of chronic high or low salt intake in the context of hypertension ...
Rebeca Caldeira Machado Berger +11 more
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