Results 51 to 60 of about 1,449,604 (285)

The Spitzer search for the transits of HARPS low-mass planets - II. Null results for 19 planets [PDF]

, 2017
Short-period super-Earths and Neptunes are now known to be very frequent around solar-type stars. Improving our understanding of these mysterious planets requires the detection of a significant sample of objects suitable for detailed characterization ...
Curto, G. Lo, Deming, D., Demory, B. -O., Ehrenreich, D., Gillon, M., Lovis, C., Mayor, M., Pepe, F., Queloz, D., Seager, S., Segransan, D., Udry, S.   +11 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Low-cost coding techniques for digital fault diagnosis [PDF]

, 1973
Published report discusses fault location properties of arithmetic codes. Criterion for effectiveness of given code is detection probability of local fault by application of checking algorithm to results of entire set of algorithms of processor.
Avizienis, A. A.
core   +1 more source

Low-Multiplicity Burst Search At The Sudbury Neutrino Observatory [PDF]

, 2011
Results are reported from a search for low-multiplicity neutrino bursts in the Sudbury Neutrino Observatory. Such bursts could indicate the detection of a nearby core-collapse supernova explosion. The data were taken from Phase I (1999 November-2001 May),
Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Boudjemline, K., Boulay, M. G., Cai, B., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Dai, X., Deng, H., Detwiler, J., Doucas, G., Drouin, P. L., Duncan, F. A., Dunford, M., Earle, E. D., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Gann, G. D. O., Goon, J. T. M., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, Paul J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jamieson, B., Jelley, N. A., Jerkins, M., Klein, J. R., Kos, M., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Law, J., Lesko, K. T., Leslie, J. R., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R., McCauley, N., McDonald, A. B., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., S. N. O. Collaboration, Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Simpson, J. J., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Tesic, G., Tolich, N., Tseung, H. W. C., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Watson, P. J. S., West, N., Wilkerson, J. F., Wilson, J. R., Wright, A., Yeh, M., Zhang, F., Zuber, K.   +109 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Opportunistic cooperative spectrum sensing based on eigenvalue ratio of random matrix

Dianxin kexue, 2020
To overcome the deficiencies of low detection probability of traditional spectrum sensing,an EROC spectrum sensing algorithm based on the eigenvalue ratio of a random matrix was proposed.Based on the random detection theory,it used double thresholds and ...
Wuji ZHANG, Shunlan LIU, Jianrong BAO
doaj   +2 more sources

LPI Radar Detection Based on Deep Learning Approach with Periodic Autocorrelation Function

Sensors, 2023
In electronic warfare systems, detecting low-probability-of-intercept (LPI) radar signals poses a significant challenge due to the signal power being lower than the noise power.
Do-Hyun Park, Min-Wook Jeon, Da-Min Shin, Hyoung-Nam Kim   +3 more
doaj   +1 more source

Prediction of deviations from the Rutherford formula for low-energy Coulomb scattering of wavepackets

, 2017
We calculate the nonrelativistic scattering of a wavepacket from a Coulomb potential and find deviations from the Rutherford formula in all cases. These generally occur only at low scattering angles, where they would be obscured by the part of the ...
Hoffmann, Scott E.
core   +1 more source