Results 21 to 30 of about 576,467 (215)

A Curvature Compensation Technique for Low-Voltage Bandgap Reference

Energies, 2021
Based on the standard 40 nm Complementary Metal Oxide Semiconductor (CMOS) process, a curvature compensation technique is proposed. Two low-voltage, low-power, high-precision bandgap voltage reference circuits are designed at a 1.2 V power supply.
Jie Shen, Houpeng Chen, Shenglan Ni, Zhitang Song   +3 more
doaj   +1 more source

Numerical Study on Low-Temperature Region as Heat Sink and Its Heat Dissipation Capacity for Hypersonic Vehicle

Aerospace, 2021
Researches have focused on the thermal protection system (TPS) of hypersonic vehicles under severe aerodynamic heat. According to the second law of thermodynamics, heat transfer needs to consume a heat sink, but the cold energy provided by the airborne ...
Xinying Jiang, Meng Liu, Hao Wu, Yonggui Zheng, Junjun Zhuang   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Design of a Bandgap Reference with a High PSRR and Strong Load-Driving Capability

Micromachines
This paper introduces an enhanced bandgap reference (BGR) design, addressing the shortcomings of traditional circuits, such as significant temperature drift, limited power-supply rejection, and inadequate load-driving capacity.
Meng Li, Lei Guo, Bin Liu, Lin Qi, Binghui He, Yu Cao, Jian Ren   +6 more
doaj   +1 more source

Tests and Analysis on Thermal Expansion Behaviour of Steel Strand used in Prestressed Concrete Structure under Low Temperatures

International Journal of Concrete Structures and Materials, 2018
This paper presents the results of the tests and analysis on the coefficient of thermal expansion for the steel strand under combined low temperatures and prestressing forces.
Jian Xie, Jia-Bao Yan
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Low-temperature curing polyimide composites with low coefficient of thermal expansion for high-temperature electronic packaging

Nano Research
Polymer materials with a wide range of applicable temperatures, excellent dielectric properties, and high reliability under complex operating conditions are imperative for packaging applications of next-generation power devices.
Tianqi Hou, Chuan He, Ying Lin, Yushun Zhao, Lijian Ding   +4 more
doaj   +1 more source

Speedup of nuclear spin diffusion in hyperpolarized solids

New Journal of Physics, 2021
We propose a correction to the coefficient of nuclear spin diffusion by a factor $1/\sqrt{1-{\bar{p}}^{2}}$ , where $\bar{p}$ is the average nuclear spin polarization.
Yu Wang, Kazuyuki Takeda
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source