Results 91 to 100 of about 13,495,511 (263)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

PERBANDINGAN PERUBAHAN HIGHER ORDER ABERRATIONS PASCA LASIK ANTARA FLAP TIPIS DAN TEBAL (Studi Observasional Longitudinal di RS Mata Undaan Surabaya) [PDF]

open access: yes, 2015
Laser assissted in situ keratomileusis (LASIK) adalah metode bedah refraktif yang diterima secara luas di seluruh dunia untuk mengkoreksi kelainan refraksi.
DIAN ARUMDINI
core   +1 more source

Calculations and Measurements of the Visual Benefit of Correcting the Higher-order Aberrations Using Adaptive Optics Technology

open access: yesJournal of Optometry, 2008
Purpose: Our goal was to examine the accuracy of metrics, calculated using a numerical eye model including the measurement of the monochromatic aberrations of the eye, to predict the contrast sensitivity (CS) and visual acuity (VA) visual benefits (VB ...
Richard Legras, Hélène Rouger
doaj   +1 more source

Monochromatic aberrations of human eyes in the horizontal visual field [PDF]

open access: yes, 2002
We measured the monochromatic aberrations of five subjects’ right eyes both temporally and nasally out to 40 degrees from fixation. We used a Hartmann–Shack sensor with modifications to equipment and software to enable\ud off-axis measurements.
Scott, Dion H., Atchison, David A.
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Visual Tasks Dependence of the Neural Compensation for the Keratoconic Eye's Optical Aberrations

open access: yesJournal of Optometry, 2010
Purpose: To investigate whether “normal” eyes viewing through keratoconic (KC) eye aberrations can achieve a similar visual performance (VP) to that of KC eyes. Method: We measured the high-contrast visual acuity (VA) and the 10, 15 and 20 c/deg contrast
Hélène Rouger   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Aberration changes of the corneal anterior surface following discontinued use of rigid gas permeable contact lenses

open access: yesInternational Journal of Ophthalmology, 2013
AIM: To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses.
Shi-Qi Dong   +5 more
doaj   +1 more source

Light sheet adaptive optics microscope for 3D live imaging [PDF]

open access: yes, 2013
Optical microscopy is still the main research tool for many biological studies. Indeed with the advent of genetic manipulation and specifically, the use of fluorescent protein expressing in animals and plants it has actually seen a renaissance in the ...
BOURGENOT, CYRIL,JULES,TUGDUAL
core  

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