Results 101 to 110 of about 13,495,511 (263)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Corneal epithelial aberrations: a novel diagnostic tool for keratoconus and forme fruste keratoconus

Eye and Vision
Purpose To assess the ability of corneal epithelial aberrations to discriminate forme fruste keratoconus (FFKC) and keratoconus (KC) from normal eyes.
Rui Ning, Chak Seng Lei, Xinning Yang, Yue Li, Yizhou Yang, Ingemar Gustafsson, Giacomo Savini, Domenico Schiano-Lomoriello, Xingtao Zhou, Xiaoying Wang, Jinhai Huang   +10 more
doaj   +1 more source

Correlations of pterygial blood flow with corneal refractive properties and higher-order aberrations: A cross-sectional OCTA study

Photodiagnosis and Photodynamic Therapy
Purpose: To evaluate the associations between pterygial blood flow density (BFD) and corneal refractive properties, including higher-order aberrations (HOAs).
Jianqin Shen, Ying Chen, Yanghong Chen, Bingzhen Gou, Jianyong Wang, Hongguang Cui   +5 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Comparative analysis of myopia correction outcomes and aberration changes between PRK and SMILE: A study based on strict refractive criteria

BMC Ophthalmology
Purpose To analyze the refractive outcomes and changes in corneal aberrations after PRK and SMILE surgeries, and to compare these two methods. Patients and methods This retrospective comparative study investigated patients aged 20–40 years who underwent ...
Bekir Küçük, Mahmut Erkam Arslan, Ender Sırakaya   +2 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The Importance of HOA Reduction Measurements to Improving Refractive Surgery Result Outcomes [Letter]

Clinical Ophthalmology
Manoj Motwani Cornea Revolution/Motwani Lasik Institute, San Diego, CA, 92121, USACorrespondence: Manoj Motwani, Cornea Revolution/Motwani LASIK Institute, 9710 Scranton Road, Suite 170, San Diego, CA, 92121, USA, Tel +1 (858) 554-0008, Email drmmlj ...
Motwani M
doaj  

Study on the Effect of Clamping Structure on Wavefront Aberration of Large-Aperture Nd:Glass Laser Amplifier

Photonics
Nd:glass has become the predominant gain medium for achieving high-energy laser outputs to the order of hundreds of joules, owing to its high energy storage capacity, capacity for large apertures, and excellent optical homogeneity.
Yangyang Chen, Lin Chen, Ting Shao, Yu Xie, Xibo Sun, Huan Pang, Qier An, Honghong Wu, Lanqin Liu   +8 more
doaj   +1 more source