Results 131 to 140 of about 327,898 (294)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Including Social Nash Equilibria in Abstract Economies [PDF]
We consider quasi-variational problems (variational problems having constraint sets depending on their own solutions) which appear in concrete economic models such as social and economic networks, financial derivative models, transportation network ...
Jacqueline Morgan, M. Beatrice Lignola
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FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Upper and lower solutions for regime-switching diffusions with applications in financial mathematics
, 2011 This paper develops a method of upper and lower solutions for a general system of second-order ordinary differential equations with two-point boundary conditions.
Liu, R. H., Eloe, Paul W.
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FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Upper and lower solutions method for a superlinear duffing equation
, 2009 In this paper, an upper and lower solutions theory for the forced superlinear Duffing equation x + f(t)x\u27 + g(t, x) = 8 a.e. t ∈ [0, T] x(0)=x(T),x\u27(0)=x\u27(T) is established, and the multiplicity of periodic solutions is discussed, where / ∈ L1([
Wang, Chengwen +2 more
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Shock Layer Behavior for Vector Boundary Value Problems and Kinks in the Lower and Upper Solutions
, 1994 We provide sufficient conditions for the existence and approximations of shock layer solutions of the weakly coupled boundary value problem ϵy′′i=ƒi(t, y)y′i+gi(t, y) i=1, ..., n,yi(a)=Ai, yi(b)=Bi, where y, ƒ, and g are n-dimensional real-valued ...
Kirschvink, S.J.
core +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source