Results 111 to 120 of about 327,898 (294)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The method of upper and lower solutions for Caratheodory n-th order differential inclusions

open access: yesElectronic Journal of Differential Equations, 2004
In this paper, we prove an existence theorem for n-th order differential inclusions under Caratheodory conditions. The existence of extremal solutions is also obtained under certain monotonicity condition of the multi-function.
Bupurao C. Dhage   +2 more
doaj  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Lower and upper solutions for elliptic problems in nonsmooth domains

open access: yes, 2008
In this paper we prove some existence results of semilinear Dirichlet problems in nonsmooth domains in presence of lower and upper solutions well-ordered or not. We first prove existence results in an abstract setting using degree theory.
De Coster, Colette, Nicaise, Serge
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Two Abstract Methods of Lower and Upper Solutions with Applications

open access: yesResults in Mathematics
Abstract In this paper, we present two abstract methods for constructing a lower and an upper solution for a fixed point equation. The first method applies when the nonlinear operator is a composition of a linear and a nonlinear mapping, while the second method applies when the nonlinear operator satisfies an inequality of Harnack ...
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Approximation of solutions for nonlinear periodic boundary value problems with discontinuous upper and lower solutions

open access: yes, 1998
We prove that it is possible to approximate the solutions of a nonlinear periodic boundary value problem via monotone sequences starting at piecewise continuous upper and lower solutions. In fact, we present here two different iterative methods. Explicit
Liz, Eduardo, Pouso, Rodrigo L.
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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